HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: RACK1 (P63244)
Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	18420585
Identification Methods	two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 317
+	Hs
		792964 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		793023 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Dm
		1096069 DYL1_DROME (1-89): 1.36e-46: 145: 94.38		FBXW7_DROME (3-128): 9.64e-20: 92: 19.53