HitPredict

Interactor 1: AAPK1 (P54645)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: Prkaa1

Interactor 2: 1433E (P62260)
14-3-3 protein epsilon (14-3-3E) (Mitochondrial import stimulation factor L subunit) (MSF L)
Gene: Ywhae

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	24625528
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030424 - axon GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Rn			1 255
+	Hs
		971469 AAPK1_HUMAN (1-559): 0: 591: 99.11		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		930668 AAPK2_HUMAN (13-559): 0: 535: 75.23		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Xl
		237424 Q8QGV3_XENLA (3-545): 1.95e-148: 447: 29.84		O57468_XENLA (1-255): 1.71e-152: 426: 96.47
+	Hs
		971697 MARK2_HUMAN (19-545): 4.17e-146: 441: 29.95		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Mm
		972209 MARK2_MOUSE (3-549): 9.15e-146: 440: 28.70		1433E_MOUSE (1-255): 4.89e-154: 430: 100.00
+	Hs
		692031 MARK3_HUMAN (2-536): 1.25e-144: 436: 28.30		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Mm
		972206 MARK3_MOUSE (19-536): 8.38e-143: 432: 28.62		1433E_MOUSE (1-255): 4.89e-154: 430: 100.00
+	Xl
		237423 Q804T2_XENLA (2-536): 6.5e-143: 431: 27.85		O57468_XENLA (1-255): 1.71e-152: 426: 96.47
+	Hs
		943639 SIK1_HUMAN (4-540): 1.66e-140: 427: 31.63		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	At
		1030913 CIPKC_ARATH (8-530): 1.33e-149: 440: 25.29		14332_ARATH (4-255): 1.05e-147: 414: 74.41
+	At
		840534 CIPKC_ARATH (8-530): 1.33e-149: 440: 25.29		14333_ARATH (1-253): 3.47e-147: 413: 74.12
+	At
		1379653 CIPKC_ARATH (8-530): 1.33e-149: 440: 25.29		14337_ARATH (2-255): 7.77e-147: 412: 71.21
+	Mm
		972284 MARK4_MOUSE (11-404): 1.48e-133: 408: 35.56		1433E_MOUSE (1-255): 4.89e-154: 430: 100.00
+	Hs
		971885 MARK4_HUMAN (11-404): 4.09e-133: 406: 35.31		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Sc
		448694 SNF1_YEAST (23-475): 5.49e-142: 425: 38.06		BMH2_YEAST (4-242): 1.15e-134: 382: 77.08
+	Sc
		448664 SNF1_YEAST (23-475): 5.49e-142: 425: 38.06		BMH1_YEAST (2-243): 2.44e-134: 381: 75.72
+	Hs
		971985 SIK2_HUMAN (10-340): 2.09e-85: 285: 42.69		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		971753 BRSK2_HUMAN (24-376): 7.35e-82: 272: 42.12		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Mm
		972247 BRSK2_MOUSE (24-376): 9.35e-82: 272: 42.12		1433E_MOUSE (1-255): 4.89e-154: 430: 100.00
+	Mm
		972223 BRSK1_MOUSE (24-279): 1.76e-80: 270: 50.78		1433E_MOUSE (1-255): 4.89e-154: 430: 100.00