HitPredict

Interactor 1: MP2K1 (Q02750)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: MAP2K1

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	15118098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 315
+	Hs
		735004 MP2K2_HUMAN (1-391): 2.96e-123: 363: 79.40		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		625202 CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		972235 MP2K1_HUMAN (1-393): 1.26e-125: 369: 100.00		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		414806 CDK1_HUMAN (65-367): 7.64e-110: 325: 26.45		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		625543 CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		681967 AKT1_HUMAN (39-389): 1.97e-120: 359: 19.44		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	At
		1105322 KIN10_ARATH (67-393): 5.73e-124: 369: 19.34		PRL1_ARATH (103-312): 2.25e-55: 188: 23.72
+	At
		955193 KIN11_ARATH (67-393): 5.27e-122: 364: 20.54		PRL1_ARATH (103-312): 2.25e-55: 188: 23.72
+	Hs
		734902 MP2K2_HUMAN (1-391): 2.96e-123: 363: 79.40		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		1027412 STK3_HUMAN (50-369): 2.6e-109: 331: 33.23		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		415016 CDK1_HUMAN (65-367): 7.64e-110: 325: 26.45		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61