HitPredict

Interactor 1: O57468 (O57468)
14-3-3 protein epsilon
Gene: ywhae.S

Interactor 2: Q8QGV3 (Q8QGV3)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (MAP/microtubule affinity-regulating kinase 2)
Gene: mark2.L

Species: Xenopus laevis

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15343271
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Xl			1 785
+	Hs
		971697 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		MARK2_HUMAN (2-785): 0: 748: 81.94
+	Mm
		972209 1433E_MOUSE (1-255): 3.02e-153: 428: 96.47		MARK2_MOUSE (2-785): 0: 733: 80.91
+	Hs
		692031 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		MARK3_HUMAN (1-785): 0: 697: 59.32
+	Mm
		972206 1433E_MOUSE (1-255): 3.02e-153: 428: 96.47		MARK3_MOUSE (1-785): 0: 696: 59.19
+	Hs
		972078 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		MARK1_HUMAN (1-785): 0: 689: 63.57
+	Mm
		972294 1433E_MOUSE (1-255): 3.02e-153: 428: 96.47		MARK1_MOUSE (1-785): 0: 684: 63.07
+	Xl
		237423 O57468_XENLA (1-255): 3.81e-152: 425: 100.00		Q804T2_XENLA (1-785): 0: 672: 57.94
+	Hs
		971885 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		MARK4_HUMAN (1-785): 0: 591: 49.25
+	Mm
		972284 1433E_MOUSE (1-255): 3.02e-153: 428: 96.47		MARK4_MOUSE (1-785): 0: 590: 49.25
+	Hs
		971530 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		MELK_HUMAN (57-785): 3.15e-167: 499: 25.34
+	Hs
		971985 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		SIK2_HUMAN (41-757): 1.15e-144: 449: 30.91
+	Mm
		972223 1433E_MOUSE (1-255): 3.02e-153: 428: 96.47		BRSK1_MOUSE (53-580): 1.32e-143: 442: 33.93
+	Hs
		943639 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		SIK1_HUMAN (35-677): 1.54e-140: 434: 31.69
+	Hs
		971469 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		AAPK1_HUMAN (31-561): 2.19e-141: 429: 28.78
+	Rn
		930528 1433E_RAT (1-255): 3.02e-153: 428: 96.47		AAPK1_RAT (32-561): 5.87e-139: 423: 29.95
+	At
		1030913 14332_ARATH (4-255): 1.37e-147: 414: 74.80		CIPKC_ARATH (38-370): 5.74e-139: 421: 37.69
+	At
		840534 14333_ARATH (1-253): 1.17e-146: 411: 74.90		CIPKC_ARATH (38-370): 5.74e-139: 421: 37.69
+	At
		1379653 14337_ARATH (4-255): 4.69e-146: 410: 72.16		CIPKC_ARATH (38-370): 5.74e-139: 421: 37.69
+	Hs
		972160 1433E_HUMAN (1-255): 3.02e-153: 428: 96.47		SIK3_HUMAN (54-384): 2.05e-108: 362: 54.87
+	Mm
		972247 1433E_MOUSE (1-255): 3.02e-153: 428: 96.47		BRSK2_MOUSE (48-478): 1.19e-78: 270: 37.72