HitPredict

Interactor 1: EPHA5 (P54756)
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)
Gene: EPHA5

Interactor 2: P55G (Q92569)
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
Gene: PIK3R3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~fn3, PK_Tyr_Ser-Thr~SH2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1037 Hs			1 461
+	Hs
		699662 EPHA5_HUMAN (1-1037): 0: 1316: 100.00		P85A_HUMAN (48-455): 1.82e-102: 323: 79.41
+	Hs
		136345 EPHA5_HUMAN (1-1037): 0: 1316: 100.00		P85B_HUMAN (56-453): 1.57e-98: 313: 74.12
+	Hs
		699596 EPHA3_HUMAN (51-1037): 0: 1168: 66.53		P85A_HUMAN (48-455): 1.82e-102: 323: 79.41
+	Hs
		699761 EPHA7_HUMAN (37-1035): 0: 1166: 61.90		P85A_HUMAN (48-455): 1.82e-102: 323: 79.41
+	Hs
		699663 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		P85A_HUMAN (48-455): 1.82e-102: 323: 79.41
+	Hs
		136300 EPHA3_HUMAN (51-1037): 0: 1168: 66.53		P85B_HUMAN (56-453): 1.57e-98: 313: 74.12
+	Hs
		136391 EPHA7_HUMAN (37-1035): 0: 1166: 61.90		P85B_HUMAN (56-453): 1.57e-98: 313: 74.12
+	Hs
		136346 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		P85B_HUMAN (56-453): 1.57e-98: 313: 74.12
+	Hs
		362173 EPHA3_HUMAN (51-1037): 0: 1168: 66.53		ABL1_HUMAN (33-461): 3.7e-93: 306: 16.59
+	Hs
		440461 EPHA5_HUMAN (1-1037): 0: 1316: 100.00		FYN_HUMAN (323-459): 5.41e-23: 103: 25.52
+	Hs
		840960 EPHA7_HUMAN (37-1035): 0: 1166: 61.90		ABL2_HUMAN (301-459): 1.22e-23: 106: 23.93
+	Hs
		440391 EPHA3_HUMAN (51-1037): 0: 1168: 66.53		FYN_HUMAN (323-459): 5.41e-23: 103: 25.52
+	Hs
		840938 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		ABL2_HUMAN (301-459): 1.22e-23: 106: 23.93
+	Hs
		440462 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		FYN_HUMAN (323-459): 5.41e-23: 103: 25.52
+	Hs
		557120 EPHA3_HUMAN (51-1037): 0: 1168: 66.53		SRC_HUMAN (324-459): 7.1e-21: 97.3: 24.31
+	Hs
		463359 EPHA3_HUMAN (51-1037): 0: 1168: 66.53		LYN_HUMAN (245-458): 1.18e-20: 96.5: 19.91
+	Hs
		463529 EPHA7_HUMAN (37-1035): 0: 1166: 61.90		LYN_HUMAN (245-458): 1.18e-20: 96.5: 19.91
+	Hs
		557189 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		SRC_HUMAN (324-459): 7.1e-21: 97.3: 24.31
+	Hs
		463419 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		LYN_HUMAN (245-458): 1.18e-20: 96.5: 19.91
+	Hs
		599278 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		PLCG2_HUMAN (337-452): 7.01e-12: 69.8: 33.33