Interactor 1: DRICE (O01382)
Caspase (EC 3.4.22.-) (drICE) [Cleaved into: Caspase subunit p21; Caspase subunit p12]
Gene: DRICE

Interactor 2: DRONC (Q9XYF4)
Caspase Dronc (EC 3.4.22.-) (NEDD2-like caspase) [Cleaved into: Caspase Nc subunit 1; Caspase Nc subunit 2]
Gene: DRONC

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 10675329, 23913920, 25644603, 20700104, 18084239, 18309328, unassigned4
Identification Methods pull down, enzymatic study, coimmunoprecipitation, protease assay, two hybrid, experimental interaction detection
Interaction Type direct interaction, physical association, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C14~Peptidase_C14
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 339
Dm

1 450
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Last updated: 15 Jul 2024