HitPredict

Interactor 1: UB2L3 (P68036)
Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)
Gene: UBE2L3

Interactor 2: VPS11 (Q9H270)
Vacuolar protein sorting-associated protein 11 homolog (hVPS11) (RING finger protein 108)
Gene: VPS11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	29643511
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0016567 - protein ubiquitination GO:1903955 - positive regulation of protein targeting to mitochondrion
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 154 Hs			1 941
+	Hs
		919861 UB2D2_HUMAN (2-149): 7.95e-75: 221: 37.58		VPS11_HUMAN (1-941): 0: 1040: 100.00
+	Sc
		522434 UBC4_YEAST (1-148): 8.58e-75: 221: 40.27		PEP5_YEAST (7-908): 0: 557: 21.50
+	Hs
		919887 UB2D2_HUMAN (2-149): 7.95e-75: 221: 37.58		VPS18_HUMAN (105-847): 1.09e-158: 493: 16.16
+	Sc
		549839 UBC4_YEAST (1-148): 8.58e-75: 221: 40.27		VAM6_YEAST (451-830): 1.86e-37: 154: 12.80