HitPredict

Interactor 1: PAR2 (P55085)
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
Gene: F2RL1

Interactor 2: Q4LE69 (Q4LE69)
Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67)
Gene: PIK4CA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 2121
+	Hs
		1195661 P2RY8_HUMAN (61-395): 2.83e-77: 244: 34.62		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		770860 OPRM_HUMAN (5-397): 1.36e-74: 239: 21.66		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		839475 P2RY8_HUMAN (61-395): 2.83e-77: 244: 34.62		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		770829 OPRM_HUMAN (5-397): 1.36e-74: 239: 21.66		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		771134 APJ_HUMAN (55-383): 1.25e-69: 225: 23.17		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		839445 PAR2_HUMAN (1-374): 4.98e-74: 237: 100.00		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		879786 NPY2R_HUMAN (61-361): 1.31e-68: 223: 16.56		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		771100 APJ_HUMAN (55-383): 1.25e-69: 225: 23.17		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		839439 NPY2R_HUMAN (61-361): 1.31e-68: 223: 16.56		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		839455 GPR17_HUMAN (57-385): 5.5e-65: 213: 28.06		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		133255 P2Y10_HUMAN (60-354): 7.97e-30: 119: 29.90		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		133232 P2Y10_HUMAN (60-354): 7.97e-30: 119: 29.90		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		839142 CXCR4_HUMAN (73-370): 5.18e-81: 254: 22.62		PK3CB_HUMAN (1465-2118): 7.14e-140: 467: 18.78
+	Hs
		877415 CXCR4_HUMAN (73-370): 5.18e-81: 254: 22.62		PK3CG_HUMAN (1522-2119): 7.19e-133: 448: 19.56
+	Mm
		1000496 CXCR4_MOUSE (73-370): 9.53e-81: 253: 22.08		PK3CG_MOUSE (1522-2119): 4.67e-131: 443: 19.87
+	Hs
		133231 P2Y10_HUMAN (60-354): 7.97e-30: 119: 29.90		PK3CB_HUMAN (1465-2118): 7.14e-140: 467: 18.78
+	Hs
		839174 LPAR5_HUMAN (80-395): 1.58e-28: 116: 28.75		PK3CB_HUMAN (1465-2118): 7.14e-140: 467: 18.78