HitPredict

Interactor 1: SOX10 (P56693)
Transcription factor SOX-10
Gene: SOX10

Interactor 2: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 1069
+	Hs
		1257103 CIC_HUMAN (34-358): 3.14e-43: 165: 19.10		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		1257119 SOX7_HUMAN (84-451): 7.66e-38: 144: 25.86		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		872459 SOX2_HUMAN (72-239): 3.75e-38: 143: 38.04		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		325212 SOX30_HUMAN (67-441): 2.89e-35: 141: 22.25		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		1257132 SOX17_HUMAN (67-337): 1.06e-34: 136: 26.95		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		873097 SOX9_HUMAN (13-466): 8.76e-34: 134: 46.94		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		942126 SOX10_HUMAN (1-466): 9.92e-65: 217: 100.00		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		1401422 CIC_HUMAN (34-358): 3.14e-43: 165: 19.10		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Mm
		59403 Q60I23_MOUSE (97-239): 9.39e-38: 142: 41.51		CHD7_MOUSE (227-893): 3.98e-37: 154: 9.58
+	Hs
		776139 SOX5_HUMAN (96-180): 2.84e-37: 147: 47.06		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		1413236 SOX7_HUMAN (84-451): 7.66e-38: 144: 25.86		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		872830 SOX2_HUMAN (72-239): 3.75e-38: 143: 38.04		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		1288003 PB1_HUMAN (1-336): 3.87e-34: 138: 12.21		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		1434979 SOX17_HUMAN (67-337): 1.06e-34: 136: 26.95		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		925743 CIC_HUMAN (34-358): 3.14e-43: 165: 19.10		SC24C_HUMAN (170-477): 1.61e-12: 74.3: 9.33
+	Hs
		321986 CIC_HUMAN (34-358): 3.14e-43: 165: 19.10		NFAT5_HUMAN (180-600): 4.55e-12: 72.7: 15.29
+	Hs
		1338269 SOX7_HUMAN (84-451): 7.66e-38: 144: 25.86		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07
+	Hs
		872546 SOX2_HUMAN (72-239): 3.75e-38: 143: 38.04		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07
+	Hs
		1338275 SOX17_HUMAN (67-337): 1.06e-34: 136: 26.95		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07
+	Hs
		873102 SOX9_HUMAN (13-466): 8.76e-34: 134: 46.94		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07