Interactor 1: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Interactor 2: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 32296183, 33961781, 34133714, 26167880, 32707033, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, enzymatic study, two hybrid array, validated two hybrid, two hybrid prey pooling approach, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
GO:0016607 - nuclear speck
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 688
Hs

1 484
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Last updated: 15 Jul 2024