HitPredict

Interactor 1: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Interactor 2: PRAF1 (Q9UI14)
Prenylated Rab acceptor protein 1 (PRA1 family protein 1)
Gene: RABAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 185
+	Hs
		981377 RAB1A_HUMAN (10-213): 9.39e-88: 258: 39.51		PRAF1_HUMAN (1-185): 5.41e-67: 204: 100.00
+	Rn
		204787 RAB1A_RAT (10-213): 9.39e-88: 258: 39.51		PRAF1_RAT (1-185): 2.61e-66: 202: 95.14
+	Hs
		631541 RAB5A_HUMAN (1-215): 1.29e-86: 256: 81.86		PRAF1_HUMAN (1-185): 5.41e-67: 204: 100.00
+	Hs
		1430486 RAB1B_HUMAN (13-213): 2.31e-86: 255: 39.30		PRAF1_HUMAN (1-185): 5.41e-67: 204: 100.00
+	Hs
		901091 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		PRAF1_HUMAN (1-185): 5.41e-67: 204: 100.00
+	Hs
		956533 RAB2A_HUMAN (17-208): 3.63e-82: 245: 37.50		PRAF1_HUMAN (1-185): 5.41e-67: 204: 100.00
+	At
		1441500 RABD1_ARATH (16-213): 3.77e-89: 262: 39.00		PR1F4_ARATH (17-182): 3.69e-52: 166: 18.68
+	At
		306628 RAE1C_ARATH (16-213): 4.62e-82: 245: 36.28		PR1B4_ARATH (27-181): 6.04e-54: 172: 24.36
+	At
		1443883 RABD1_ARATH (16-213): 3.77e-89: 262: 39.00		PR1B6_ARATH (33-184): 5.43e-47: 154: 26.14
+	At
		1456647 RABD1_ARATH (16-213): 3.77e-89: 262: 39.00		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	At
		701376 RAE1C_ARATH (16-213): 4.62e-82: 245: 36.28		PR1F3_ARATH (17-182): 6.88e-48: 156: 18.07
+	At
		201161 RAE1A_ARATH (16-213): 1.77e-82: 246: 37.75		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	At
		701377 RAE1C_ARATH (16-213): 4.62e-82: 245: 36.28		PR1B6_ARATH (33-184): 5.43e-47: 154: 26.14
+	At
		727478 RAF2A_ARATH (22-186): 1.29e-76: 230: 70.30		PR1B5_ARATH (21-181): 3.42e-52: 168: 22.22
+	Hs
		297173 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		PRAF3_HUMAN (39-185): 1.57e-39: 134: 21.85
+	Sc
		376327 YPT1_YEAST (14-213): 1.04e-89: 263: 41.46		PRA1_YEAST (16-179): 9.53e-35: 122: 25.30
+	At
		727480 RAF2A_ARATH (22-186): 1.29e-76: 230: 70.30		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	Hs
		257621 RAB1A_HUMAN (10-213): 9.39e-88: 258: 39.51		PRAF2_HUMAN (36-185): 8.82e-32: 114: 20.13
+	Hs
		257613 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		PRAF2_HUMAN (36-185): 8.82e-32: 114: 20.13
+	Sc
		779624 VPS21_YEAST (16-188): 9.29e-64: 198: 59.55		PRA1_YEAST (16-179): 9.53e-35: 122: 25.30