HitPredict

Interactor 1: SHC2 (P98077)
SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2)
Gene: SHC2

Interactor 2: Q6NSK7 (Q6NSK7)
RIN3 protein
Gene: RIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 908
+	Hs
		666139 SHC1_HUMAN (1-581): 2.34e-124: 379: 45.41		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		557717 NCK1_HUMAN (456-574): 4.57e-35: 137: 24.59		Q6NSK7_HUMAN (1-908): 0: 678: 100.00
+	Hs
		1251876 ANS1A_HUMAN (34-384): 4.52e-50: 188: 14.91		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		523075 SRC_HUMAN (326-573): 4.48e-39: 152: 15.06		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		1191809 ANS1B_HUMAN (26-360): 3.45e-51: 192: 13.11		RIN2_HUMAN (15-885): 0: 553: 32.62
+	Hs
		411796 LCK_HUMAN (321-582): 1.49e-36: 144: 14.60		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		557745 NCK1_HUMAN (456-574): 4.57e-35: 137: 24.59		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		70370 B2R6S4_HUMAN (456-574): 4.57e-35: 137: 24.59		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		69536 B0LPF3_HUMAN (475-582): 5.69e-16: 79.1: 28.07		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		855796 VAV2_HUMAN (380-578): 2.05e-36: 147: 13.74		GAPD1_HUMAN (155-765): 1.05e-73: 267: 15.97
+	Hs
		1044774 Q49AR9_HUMAN (34-487): 1.89e-54: 195: 12.92		RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18
+	Hs
		1044783 ANS1B_HUMAN (26-360): 3.45e-51: 192: 13.11		RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18
+	Hs
		1044796 ANS1A_HUMAN (34-384): 4.52e-50: 188: 14.91		RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18
+	Hs
		1044790 SH2D3_HUMAN (362-580): 2.17e-38: 153: 19.57		RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18
+	Hs
		523025 SRC_HUMAN (326-573): 4.48e-39: 152: 15.06		TENS3_HUMAN (26-185): 2.03e-29: 128: 15.08
+	Hs
		655419 P85A_HUMAN (427-578): 3.1e-23: 106: 19.23		TENS4_HUMAN (7-158): 1.34e-29: 128: 16.46
+	Hs
		924632 GRB2_HUMAN (475-582): 5.69e-16: 79.1: 28.07		TENS2_HUMAN (3-217): 4.89e-32: 137: 19.33
+	Hs
		203198 LCK_HUMAN (321-582): 1.49e-36: 144: 14.60		SYNJ1_HUMAN (103-493): 8.16e-10: 65.2: 14.14
+	Hs
		203208 NCK1_HUMAN (456-574): 4.57e-35: 137: 24.59		SYNJ1_HUMAN (103-493): 8.16e-10: 65.2: 14.14
+	Hs
		203218 GRB2_HUMAN (475-582): 5.69e-16: 79.1: 28.07		SYNJ1_HUMAN (103-493): 8.16e-10: 65.2: 14.14