HitPredict

Interactor 1: DAB2 (P98082)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)
Gene: DAB2

Interactor 2: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16101684
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0038024 - cargo receptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 770 Hs			1 963
+	Hs
		957165 DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Hs
		270287 DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00		LRP6_HUMAN (253-435): 5.25e-09: 62.6: 16.04
+	Hs
		351065 DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00		LDLR_HUMAN (683-895): 4.15e-09: 62.6: 10.65
+	Hs
		957171 DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00		LRP1_HUMAN (5-257): 6.13e-09: 62.6: 13.53
+	Mm
		57554 DAB2_MOUSE (1-770): 1.47e-81: 278: 82.15		LRP2_MOUSE (195-462): 9.58e-10: 65.3: 17.36
+	Rn
		292326 DAB2_RAT (1-770): 2.88e-78: 269: 80.34		LRP2_RAT (195-462): 4.71e-10: 66: 18.06
+	Mm
		956222 DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27		VLDLR_MOUSE (5-232): 7.68e-31: 132: 24.61
+	Mm
		956234 DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27		LRP8_MOUSE (4-333): 1.96e-29: 128: 27.04
+	Mm
		729617 DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27		LDLR_MOUSE (6-232): 2.8e-26: 118: 21.62
+	Hs
		992719 GULP1_HUMAN (20-342): 1.71e-62: 213: 20.00		LRP1_HUMAN (5-257): 6.13e-09: 62.6: 13.53
+	Mm
		69879 DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27		B1AXJ3_MOUSE (5-230): 2.86e-23: 108: 17.30
+	Hs
		957612 ARH_HUMAN (13-293): 3.15e-56: 197: 13.54		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Hs
		351073 ARH_HUMAN (13-293): 3.15e-56: 197: 13.54		LDLR_HUMAN (683-895): 4.15e-09: 62.6: 10.65
+	Mm
		57558 ARH_MOUSE (13-293): 1.1e-53: 190: 13.94		LRP2_MOUSE (195-462): 9.58e-10: 65.3: 17.36
+	Rn
		88518 ARH_RAT (13-293): 4.42e-51: 182: 13.94		LRP2_RAT (195-462): 4.71e-10: 66: 18.06
+	Hs
		957621 ANS1B_HUMAN (12-227): 1.36e-43: 172: 19.01		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Hs
		992682 ANS1B_HUMAN (12-227): 1.36e-43: 172: 19.01		LRP1_HUMAN (5-257): 6.13e-09: 62.6: 13.53
+	Mm
		956233 DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27		LRP1_MOUSE (690-894): 6.6e-10: 65.6: 11.16
+	Mm
		57553 DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27		LRP2_MOUSE (195-462): 9.58e-10: 65.3: 17.36
+	Hs
		269114 DAB1_HUMAN (16-597): 1.41e-40: 159: 24.62		LDLR_HUMAN (683-895): 4.15e-09: 62.6: 10.65