HitPredict

Interactor 1: E7EQY4 (E7EQY4)
Metastasis-associated protein MTA3
Gene: MTA3

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 514 Hs			1 482
+	Hs
		1110039 MTA3_HUMAN (1-511): 0: 668: 99.02		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1368092 MTA3_HUMAN (1-511): 0: 668: 99.02		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Mm
		148724 MTA1_MOUSE (1-512): 0: 601: 72.64		HDAC1_MOUSE (1-482): 0: 672: 99.38
+	Mm
		148739 MTA2_MOUSE (1-512): 0: 600: 69.32		HDAC1_MOUSE (1-482): 0: 672: 99.38
+	Hs
		1102528 MTA1_HUMAN (1-512): 0: 602: 73.02		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1102617 MTA1_HUMAN (1-512): 0: 602: 73.02		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Mm
		1000031 MTA1_MOUSE (1-512): 0: 601: 72.64		HDAC2_MOUSE (1-478): 0: 664: 85.71
+	Hs
		316845 MTA2_HUMAN (1-512): 0: 597: 69.32		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Mm
		1000040 MTA2_MOUSE (1-512): 0: 600: 69.32		HDAC2_MOUSE (1-478): 0: 664: 85.71
+	Hs
		316935 MTA2_HUMAN (1-512): 0: 597: 69.32		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Dm
		84936 B7Z0T5_DROME (10-513): 1.07e-180: 531: 49.00		HDAC1_DROME (6-477): 0: 658: 77.33
+	Mm
		148713 RERE_MOUSE (5-514): 1.65e-129: 413: 23.17		HDAC1_MOUSE (1-482): 0: 672: 99.38
+	Hs
		1110139 RERE_HUMAN (5-514): 1.08e-126: 405: 23.00		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1368170 RERE_HUMAN (5-514): 1.08e-126: 405: 23.00		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1109880 RCOR2_HUMAN (137-514): 1.25e-77: 254: 18.78		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Mm
		1000028 RCOR2_MOUSE (137-514): 1.55e-78: 257: 18.78		HDAC2_MOUSE (1-478): 0: 664: 85.71
+	Hs
		1315917 RCOR2_HUMAN (137-514): 1.25e-77: 254: 18.78		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1109999 TREF1_HUMAN (121-468): 1.93e-69: 243: 17.32		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1110137 RCOR3_HUMAN (150-514): 1.22e-69: 232: 15.55		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		188379 RCOR3_HUMAN (150-514): 1.22e-69: 232: 15.55		HDAC3_HUMAN (9-434): 0: 574: 57.94