HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: DEP1B (Q8WUY9)
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)
Gene: DEPDC1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Hs			1 529
+	Hs
		910147 RND2_HUMAN (20-244): 3.92e-103: 300: 64.00		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		1357399 RND1_HUMAN (1-244): 2.92e-100: 293: 58.20		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		466385 RHOC_HUMAN (22-213): 1.28e-92: 272: 49.48		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		978198 RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		978233 RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84		DEPD7_HUMAN (6-489): 3.49e-112: 344: 23.62
+	Hs
		67604 RHOC_HUMAN (22-213): 1.28e-92: 272: 49.48		RHG32_HUMAN (147-497): 3.7e-60: 217: 14.58
+	Hs
		67648 RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84		RHG32_HUMAN (147-497): 3.7e-60: 217: 14.58
+	Hs
		978083 RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84		RHG17_HUMAN (140-508): 4.1e-57: 206: 14.02
+	Hs
		978145 RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84		RHG12_HUMAN (78-393): 5.87e-56: 203: 15.74
+	Hs
		65907 RAC1_HUMAN (24-210): 3.64e-80: 240: 43.32		RHG42_HUMAN (58-504): 4.76e-62: 220: 12.79
+	Mm
		988896 RAC1_MOUSE (24-210): 3.64e-80: 240: 43.32		CHIO_MOUSE (102-393): 2.6e-66: 219: 10.92
+	Mm
		988897 RAC1_MOUSE (24-210): 3.64e-80: 240: 43.32		RHG32_MOUSE (147-497): 1.43e-60: 218: 14.58
+	Hs
		67650 RAC1_HUMAN (24-210): 3.64e-80: 240: 43.32		RHG32_HUMAN (147-497): 3.7e-60: 217: 14.58
+	Mm
		988900 RAC1_MOUSE (24-210): 3.64e-80: 240: 43.32		RHG22_MOUSE (93-427): 1.21e-56: 203: 12.97
+	Dm
		870516 RHO1_DROME (25-207): 2.67e-82: 245: 49.73		CONU_DROME (252-430): 3.82e-50: 183: 18.48
+	Hs
		978157 RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84		RHG18_HUMAN (194-416): 3.99e-38: 150: 16.39
+	Dm
		870525 RHO1_DROME (25-207): 2.67e-82: 245: 49.73		Q9VFK2_DROME (193-423): 1.98e-42: 164: 17.72
+	Hs
		978069 RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84		DEP1A_HUMAN (323-517): 1.89e-32: 134: 54.87
+	Ce
		98436 RHO1_CAEEL (22-200): 2.1e-93: 274: 50.28		F0IWT2_CAEEL (232-404): 8.61e-18: 89.5: 18.50
+	Sp
		207213 RHO1_SCHPO (21-216): 1.02e-90: 267: 48.98		RGA1_SCHPO (229-508): 1.96e-18: 91.4: 14.63