HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 974
+	Hs
		964797 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		WDR5_HUMAN (180-471): 1.59e-45: 169: 14.62
+	Hs
		965071 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		WDR5B_HUMAN (2-175): 4.36e-41: 156: 13.19
+	Hs
		965141 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		FBXW7_HUMAN (219-506): 2.83e-22: 104: 12.93
+	Hs
		965194 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		GRWD1_HUMAN (96-354): 6.15e-21: 99.1: 16.60
+	Hs
		209230 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		PRP4_HUMAN (10-133): 6.61e-19: 93.3: 14.52
+	Hs
		964891 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		RBBP4_HUMAN (145-377): 1.33e-17: 88.4: 20.39
+	Hs
		965276 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		NLE1_HUMAN (3-88): 2.28e-17: 88.3: 7.78
+	Hs
		965151 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		SNR40_HUMAN (268-503): 2.32e-17: 86.8: 8.71
+	Hs
		845264 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		LIS1_HUMAN (278-536): 1.85e-16: 84.9: 8.49
+	Hs
		222461 PLRG1_HUMAN (2-333): 4.67e-85: 267: 26.05		WDR5_HUMAN (180-471): 1.59e-45: 169: 14.62
+	Dm
		1463921 Q9VYQ9_DROME (12-333): 2.57e-94: 290: 26.67		WDS_DROME (223-440): 4.73e-27: 116: 11.21
+	Dm
		1463899 WDS_DROME (3-290): 6.4e-92: 279: 31.21		WDS_DROME (223-440): 4.73e-27: 116: 11.21
+	Mm
		988931 LIS1_MOUSE (2-289): 6.65e-95: 289: 29.49		LIS1_MOUSE (278-536): 1.67e-16: 84.9: 8.49
+	Hs
		845250 LIS1_HUMAN (2-289): 9.62e-95: 288: 29.49		LIS1_HUMAN (278-536): 1.85e-16: 84.9: 8.49
+	Ce
		1018728 LIS1_CAEEL (2-289): 5.9e-87: 268: 24.68		LIN53_CAEEL (104-371): 8.18e-17: 86.1: 19.07
+	Hs
		222515 PLRG1_HUMAN (2-333): 4.67e-85: 267: 26.05		SNR40_HUMAN (268-503): 2.32e-17: 86.8: 8.71
+	Hs
		1334151 POC1B_HUMAN (5-251): 2.76e-84: 264: 27.89		POC1A_HUMAN (268-629): 1.08e-17: 88.7: 9.79
+	Hs
		1387527 WDR83_HUMAN (25-333): 4.3e-84: 258: 31.83		SNR40_HUMAN (268-503): 2.32e-17: 86.8: 8.71