HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: WDTC1 (Q8N5D0)
WD and tetratricopeptide repeats protein 1
Gene: WDTC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 677
+	Hs
		965002 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		DCAF6_HUMAN (479-669): 1.62e-40: 161: 29.85
+	Hs
		964894 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		TBL3_HUMAN (11-323): 3.43e-32: 135: 11.37
+	Hs
		845264 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		LIS1_HUMAN (494-670): 2.41e-24: 107: 9.89
+	Hs
		921858 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		COPA_HUMAN (5-202): 3.65e-20: 97.9: 14.14
+	Hs
		965276 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		NLE1_HUMAN (486-655): 1.66e-18: 91: 11.86
+	Hs
		965151 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		SNR40_HUMAN (5-118): 1.48e-18: 89.9: 21.67
+	Hs
		964797 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		WDR5_HUMAN (527-670): 2.13e-18: 89.1: 12.75
+	Hs
		222461 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		PLRG1_HUMAN (450-610): 1.01e-09: 63.4: 14.29
+	Hs
		965071 WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00		WDR5B_HUMAN (551-649): 1.15e-09: 62.5: 17.00
+	Hs
		845361 LIS1_HUMAN (2-289): 9.62e-95: 288: 29.49		CHIP_HUMAN (357-493): 1.72e-38: 146: 30.66
+	Mm
		988931 LIS1_MOUSE (2-289): 6.65e-95: 289: 29.49		LIS1_MOUSE (494-670): 2.12e-24: 108: 9.89
+	Hs
		845250 LIS1_HUMAN (2-289): 9.62e-95: 288: 29.49		LIS1_HUMAN (494-670): 2.41e-24: 107: 9.89
+	Dm
		1463921 Q9VYQ9_DROME (12-333): 2.57e-94: 290: 26.67		WDS_DROME (527-670): 1.19e-17: 87.2: 12.75
+	Dm
		1463899 WDS_DROME (3-290): 6.4e-92: 279: 31.21		WDS_DROME (527-670): 1.19e-17: 87.2: 12.75
+	Hs
		222515 PLRG1_HUMAN (2-333): 4.67e-85: 267: 26.05		SNR40_HUMAN (5-118): 1.48e-18: 89.9: 21.67
+	Hs
		1387527 WDR83_HUMAN (25-333): 4.3e-84: 258: 31.83		SNR40_HUMAN (5-118): 1.48e-18: 89.9: 21.67
+	Hs
		1334151 POC1B_HUMAN (5-251): 2.76e-84: 264: 27.89		POC1A_HUMAN (3-74): 2.68e-12: 71: 19.44