HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: LHX8 (Q68G74)
LIM/homeobox protein Lhx8 (LIM homeobox protein 8)
Gene: LHX8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 356
+	Hs
		1229379 LHX8_HUMAN (23-158): 3.97e-48: 160: 39.71		LHX6_HUMAN (15-344): 3.95e-63: 207: 55.72
+	Hs
		1229366 LHX8_HUMAN (23-158): 3.97e-48: 160: 39.71		ISL2_HUMAN (62-314): 5.99e-55: 185: 32.21
+	Hs
		961474 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		ISL1_HUMAN (62-336): 3.05e-57: 191: 30.10
+	Hs
		965498 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		ISL2_HUMAN (62-314): 5.99e-55: 185: 32.21
+	Hs
		961488 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		ISL2_HUMAN (62-314): 5.99e-55: 185: 32.21
+	Hs
		682018 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		RBTN1_HUMAN (75-194): 6.48e-54: 176: 39.02
+	Ce
		110437 LIN11_CAEEL (7-156): 1.73e-39: 139: 29.14		LIM7_CAEEL (26-284): 1.08e-49: 174: 28.44
+	Ce
		110438 HM14_CAEEL (1-157): 2.88e-39: 137: 28.30		LIM7_CAEEL (26-284): 1.08e-49: 174: 28.44
+	Ce
		478965 HM14_CAEEL (1-157): 2.88e-39: 137: 28.30		MEC3_CAEEL (50-282): 4.73e-50: 171: 24.18
+	Dm
		1477947 Q9VJ37_DROME (21-141): 2.9e-48: 165: 41.46		Q9VJ00_DROME (13-130): 8.92e-20: 92.3: 17.60
+	Dm
		120439 P92031_DROME (21-141): 3.65e-48: 164: 41.46		M9PD53_DROME (13-130): 6.75e-20: 92.6: 17.60
+	Dm
		118261 Q9VJ37_DROME (21-141): 2.9e-48: 165: 41.46		M9NCY1_DROME (13-130): 1.62e-19: 90.7: 17.60
+	Mm
		965532 LMO4_MOUSE (1-165): 8.51e-43: 141: 100.00		LMO4_MOUSE (75-186): 4.31e-25: 101: 44.35
+	Hs
		965497 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		LHX4_HUMAN (13-129): 2.7e-21: 95.7: 16.13
+	Hs
		253020 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		LMX1B_HUMAN (15-130): 3.04e-21: 95.7: 15.57
+	Hs
		961485 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		LMX1A_HUMAN (15-130): 2.92e-21: 95.7: 16.39
+	Hs
		961487 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		LHX4_HUMAN (13-129): 2.7e-21: 95.7: 16.13
+	Mm
		895872 ISL1_MOUSE (22-162): 8.36e-39: 136: 36.55		LHX3_MOUSE (3-129): 1.04e-19: 91.5: 17.16
+	Hs
		961493 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		LHX3_HUMAN (3-129): 1.22e-19: 91.1: 17.16
+	Ce
		629520 HM14_CAEEL (1-157): 2.88e-39: 137: 28.30		HM14_CAEEL (15-137): 7.27e-16: 79.5: 18.32