HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome subunit alpha-5) (alpha-5) (Proteasome zeta chain)
Gene: PSMA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA~Proteasome_A_N
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 241
+	Dm
		874988 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA5_DROME (1-241): 1.01e-103: 302: 70.37
+	Dm
		821820 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA2_DROME (3-241): 1.56e-99: 291: 31.38
+	Hs
		610234 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA5_HUMAN (1-241): 1.06e-107: 312: 100.00
+	Hs
		700565 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA5_HUMAN (1-241): 1.06e-107: 312: 100.00
+	Dm
		1376921 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSA5_DROME (1-241): 1.01e-103: 302: 70.37
+	Hs
		97059 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA1_HUMAN (3-241): 7.76e-89: 265: 28.81
+	Hs
		97060 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA2_HUMAN (3-241): 2.39e-89: 265: 30.96
+	Dm
		821881 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSA2_DROME (3-241): 1.56e-99: 291: 31.38
+	Hs
		97073 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA6_HUMAN (4-241): 1.52e-88: 263: 25.93
+	Hs
		165253 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA7_HUMAN (8-239): 5.33e-89: 265: 36.17
+	Hs
		610227 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA1_HUMAN (3-241): 7.76e-89: 265: 28.81
+	Hs
		610228 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA2_HUMAN (3-241): 2.39e-89: 265: 30.96
+	Hs
		610283 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA6_HUMAN (4-241): 1.52e-88: 263: 25.93
+	Sc
		735913 PRS6A_YEAST (24-301): 2.46e-68: 220: 65.85		PSA5_YEAST (1-241): 5.66e-95: 280: 60.49
+	Hs
		165277 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA7_HUMAN (8-239): 5.33e-89: 265: 36.17
+	Hs
		680794 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA1_HUMAN (3-241): 7.76e-89: 265: 28.81
+	Hs
		681115 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA2_HUMAN (3-241): 2.39e-89: 265: 30.96
+	Hs
		778646 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA6_HUMAN (4-241): 1.52e-88: 263: 25.93
+	Sp
		785694 PRS4_SCHPO (51-301): 6.16e-85: 263: 38.04		PSA4_SCHPO (6-241): 6.85e-44: 150: 34.03
+	Sc
		661392 PRS6A_YEAST (24-301): 2.46e-68: 220: 65.85		PSA3_YEAST (8-238): 3.61e-44: 150: 36.40