HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: NUAK1 (Q641K5)
NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (Omphalocele kinase 1)
Gene: NUAK1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16944949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Mm			1 658
+	Hs
		244241 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		NUAK1_HUMAN (1-658): 0: 579: 90.79
+	Hs
		971981 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		NUAK2_HUMAN (8-658): 1.57e-158: 471: 51.66
+	Hs
		692031 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MARK3_HUMAN (1-641): 5.54e-145: 441: 24.61
+	Mm
		972206 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		MARK3_MOUSE (1-641): 3.62e-144: 439: 24.77
+	Xl
		237423 O57468_XENLA (1-255): 1.71e-152: 426: 96.47		Q804T2_XENLA (1-654): 2.53e-144: 438: 25.52
+	Hs
		971697 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MARK2_HUMAN (5-635): 3.85e-142: 434: 26.05
+	Xl
		237424 O57468_XENLA (1-255): 1.71e-152: 426: 96.47		Q8QGV3_XENLA (5-640): 2.51e-142: 435: 25.54
+	Mm
		972209 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		MARK2_MOUSE (5-635): 1.08e-140: 431: 25.78
+	Mm
		972284 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		MARK4_MOUSE (5-633): 4.08e-140: 428: 26.66
+	Hs
		971885 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MARK4_HUMAN (6-633): 1.79e-139: 427: 26.24
+	At
		1030844 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CDPK1_ARATH (8-463): 4.83e-141: 426: 25.64
+	At
		854983 14334_ARATH (4-255): 2.52e-145: 408: 73.62		CDPK1_ARATH (8-463): 4.83e-141: 426: 25.64
+	At
		1030913 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CIPKC_ARATH (25-312): 3.75e-133: 402: 37.33
+	At
		840534 14333_ARATH (1-253): 3.47e-147: 413: 74.12		CIPKC_ARATH (25-312): 3.75e-133: 402: 37.33
+	At
		1379653 14337_ARATH (2-255): 7.77e-147: 412: 71.21		CIPKC_ARATH (25-312): 3.75e-133: 402: 37.33
+	Rn
		930528 1433E_RAT (1-255): 4.89e-154: 430: 100.00		AAPK1_RAT (38-306): 9.63e-71: 241: 47.99
+	Hs
		971469 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		AAPK1_HUMAN (38-306): 9.63e-71: 241: 47.99
+	Hs
		972160 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		SIK3_HUMAN (36-310): 8.31e-67: 240: 45.65
+	Hs
		943639 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		SIK1_HUMAN (56-307): 4.04e-68: 239: 47.43
+	Hs
		930668 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		AAPK2_HUMAN (44-306): 6.2e-69: 236: 47.17