HitPredict

Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	17043677, unassigned1973, 35709258
Identification Methods	two hybrid, two hybrid fragment pooling approach, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 7570 Hs			1 703
+	Hs
		724786 DYST_HUMAN (1-7570): 0: 2600: 100.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		974117 DYST_HUMAN (1-7570): 0: 2600: 100.00		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		974137 DYST_HUMAN (1-7570): 0: 2600: 100.00		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		963396 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		1298096 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		164656 SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Mm
		513799 DMD_MOUSE (287-1683): 1.65e-19: 100: 10.85		DEUP1_MOUSE (8-523): 3.71e-62: 220: 27.78
+	Hs
		521484 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148339 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		724781 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		725073 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148690 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		164575 SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		149428 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		963381 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		110636 H3BPE1_HUMAN (274-1767): 5.34e-16: 89.4: 9.72		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148142 SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		164647 SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		148786 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		522612 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		MYH7_HUMAN (367-695): 1.25e-09: 64: 10.00