HitPredict

Interactor 1: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Interactor 2: KLF12 (Q9Y4X4)
Krueppel-like factor 12 (Transcriptional repressor AP-2rep)
Gene: KLF12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 773 Hs			1 402
+	Hs
		884133 TLE1_HUMAN (8-773): 0: 580: 86.27		KLF3_HUMAN (20-402): 3.5e-72: 231: 38.48
+	Hs
		884134 TLE3_HUMAN (8-773): 0: 539: 80.90		KLF3_HUMAN (20-402): 3.5e-72: 231: 38.48
+	Hs
		980601 TLE1_HUMAN (8-773): 0: 580: 86.27		KLF5_HUMAN (296-399): 7.13e-45: 162: 76.92
+	Hs
		204165 TLE1_HUMAN (8-773): 0: 580: 86.27		KLF4_HUMAN (298-399): 1.24e-37: 144: 66.67
+	Hs
		980748 TLE3_HUMAN (8-773): 0: 539: 80.90		KLF5_HUMAN (296-399): 7.13e-45: 162: 76.92
+	Hs
		316865 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		KLF8_HUMAN (38-399): 4.58e-105: 316: 44.11
+	Hs
		993504 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		ZN383_HUMAN (57-401): 4.25e-92: 287: 17.26
+	Hs
		884139 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		KLF3_HUMAN (20-402): 3.5e-72: 231: 38.48
+	Hs
		903644 WDR5_HUMAN (658-772): 3.81e-36: 141: 21.37		KLF12_HUMAN (1-402): 3.29e-117: 348: 100.00
+	Hs
		993418 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		KLF5_HUMAN (296-399): 7.13e-45: 162: 76.92
+	Ce
		137695 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		KLF1_CAEEL (314-399): 8.44e-36: 139: 73.26
+	Hs
		993414 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		KLF1_HUMAN (294-400): 1.57e-40: 149: 65.74
+	Hs
		204169 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		KLF4_HUMAN (298-399): 1.24e-37: 144: 66.67
+	Hs
		884122 WDR5_HUMAN (658-772): 3.81e-36: 141: 21.37		KLF3_HUMAN (20-402): 3.5e-72: 231: 38.48
+	Hs
		157841 TBL1X_HUMAN (572-772): 8.38e-46: 174: 15.60		KLF11_HUMAN (284-400): 1.25e-30: 124: 56.41
+	Hs
		1315361 GBB4_HUMAN (439-647): 2.61e-43: 161: 19.72		KLF16_HUMAN (317-399): 2.04e-29: 116: 65.06
+	Hs
		903489 WDR5_HUMAN (658-772): 3.81e-36: 141: 21.37		KLF16_HUMAN (317-399): 2.04e-29: 116: 65.06
+	Hs
		158029 TBL1R_HUMAN (651-770): 4.06e-20: 96.4: 13.24		KLF11_HUMAN (284-400): 1.25e-30: 124: 56.41
+	Hs
		1281563 SNR40_HUMAN (510-690): 4.15e-10: 64.3: 27.98		ZKSC4_HUMAN (246-375): 1.35e-31: 127: 20.50
+	Hs
		921591 GBB2_HUMAN (689-772): 2.72e-14: 76.8: 16.47		SP6_HUMAN (294-399): 1.58e-24: 105: 47.17