HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: PKHG2 (Q9H7P9)
Pleckstrin homology domain-containing family G member 2 (PH domain-containing family G member 2)
Gene: PLEKHG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	27765816, 18045877
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 1386
+	Hs
		984227 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		ARHG2_HUMAN (7-762): 3.89e-104: 357: 14.24
+	Hs
		176741 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		MCF2L_HUMAN (23-610): 1.8e-97: 341: 21.56
+	Hs
		533817 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		MCF2_HUMAN (22-508): 2.26e-89: 313: 19.73
+	Hs
		984282 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		ECT2_HUMAN (2-497): 5e-79: 283: 21.28
+	Hs
		1436485 GBB4_HUMAN (1-340): 2.62e-106: 316: 90.88		ECT2_HUMAN (2-497): 5e-79: 283: 21.28
+	Hs
		983580 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		ECT2_HUMAN (2-497): 5e-79: 283: 21.28
+	Hs
		238811 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		KALRN_HUMAN (3-657): 5.86e-76: 281: 18.10
+	Hs
		597370 GBB3_HUMAN (1-340): 1.16e-105: 314: 83.24		ECT2_HUMAN (2-497): 5e-79: 283: 21.28
+	Hs
		1350213 NLE1_HUMAN (46-340): 4.02e-88: 274: 21.22		PREX1_HUMAN (40-427): 2.18e-84: 307: 25.29
+	Hs
		965139 WDR5_HUMAN (130-340): 4.37e-68: 218: 27.23		ARHG2_HUMAN (7-762): 3.89e-104: 357: 14.24
+	Hs
		965250 WDR5_HUMAN (130-340): 4.37e-68: 218: 27.23		ECT2_HUMAN (2-497): 5e-79: 283: 21.28
+	Hs
		1387565 SNR40_HUMAN (130-340): 1.13e-60: 199: 24.30		ECT2_HUMAN (2-497): 5e-79: 283: 21.28