HitPredict

Interactor 1: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 484 Hs			1 344
+	Hs
		984058 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		984063 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Hs
		984059 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		992756 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		993706 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		1028642 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		1037875 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23
+	Hs
		1028893 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		1031405 TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		516609 TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		965152 ANK2_HUMAN (209-479): 7.77e-09: 60.7: 19.57		PABP3_HUMAN (101-191): 1.24e-10: 64.5: 19.79
+	Hs
		951949 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84