HitPredict

Interactor 1: F1D8N6 (F1D8N6)
Nuclear receptor subfamily 4 group A member 2
Gene: NR4A2

Interactor 2: CDN2D (P55273)
Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)
Gene: CDKN2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 598 Hs			1 166
+	Hs
		848097 NR4A2_HUMAN (1-598): 3.84e-178: 519: 100.00		CDN2D_HUMAN (1-166): 9.07e-52: 164: 100.00
+	Hs
		652481 NR4A1_HUMAN (1-598): 1.1e-127: 389: 49.68		CDN2D_HUMAN (1-166): 9.07e-52: 164: 100.00
+	Hs
		937489 NR4A3_HUMAN (1-598): 1.94e-120: 371: 51.25		CDN2D_HUMAN (1-166): 9.07e-52: 164: 100.00
+	Hs
		396730 ESR1_HUMAN (107-592): 4.53e-111: 346: 23.23		EHMT2_HUMAN (11-164): 2.05e-42: 152: 23.27
+	Hs
		520541 RARA_HUMAN (173-594): 5.74e-108: 334: 28.30		CDN2D_HUMAN (1-166): 9.07e-52: 164: 100.00
+	Hs
		1367039 ESR2_HUMAN (129-592): 1.31e-107: 335: 23.44		EHMT2_HUMAN (11-164): 2.05e-42: 152: 23.27
+	Hs
		397197 ESR1_HUMAN (107-592): 4.53e-111: 346: 23.23		KDIS_HUMAN (2-142): 4.6e-36: 133: 23.29
+	Hs
		397101 ESR1_HUMAN (107-592): 4.53e-111: 346: 23.23		RAI14_HUMAN (5-142): 1.92e-34: 128: 25.18
+	Hs
		1367454 ESR2_HUMAN (129-592): 1.31e-107: 335: 23.44		RAI14_HUMAN (5-142): 1.92e-34: 128: 25.18
+	Hs
		1055666 ESR2_HUMAN (129-592): 1.31e-107: 335: 23.44		GABP1_HUMAN (42-164): 2.16e-34: 126: 29.84
+	Hs
		1347270 ESR2_HUMAN (129-592): 1.31e-107: 335: 23.44		GABP2_HUMAN (42-164): 9.41e-34: 124: 29.84
+	Hs
		396973 ESR1_HUMAN (107-592): 4.53e-111: 346: 23.23		EHMT1_HUMAN (2-120): 5.57e-28: 110: 20.83
+	Hs
		404432 GCR_HUMAN (2-597): 1.22e-103: 332: 18.72		EHMT1_HUMAN (2-120): 5.57e-28: 110: 20.83
+	Hs
		403934 GCR_HUMAN (2-597): 1.22e-103: 332: 18.72		DAPK1_HUMAN (46-165): 2.05e-27: 108: 23.58
+	Hs
		404438 GCR_HUMAN (2-597): 1.22e-103: 332: 18.72		TANC2_HUMAN (23-163): 2.13e-23: 97.5: 18.97
+	Hs
		520606 RARA_HUMAN (173-594): 5.74e-108: 334: 28.30		HACE1_HUMAN (2-97): 2.36e-20: 88.9: 24.74
+	Hs
		533228 RARB_HUMAN (173-594): 9.71e-108: 333: 27.36		HACE1_HUMAN (2-97): 2.36e-20: 88.9: 24.74
+	Hs
		1295516 ESR2_HUMAN (129-592): 1.31e-107: 335: 23.44		MIB1_HUMAN (4-114): 1.06e-17: 80.9: 20.92
+	Hs
		404191 GCR_HUMAN (2-597): 1.22e-103: 332: 18.72		MIB1_HUMAN (4-114): 1.06e-17: 80.9: 20.92
+	Hs
		404230 GCR_HUMAN (2-597): 1.22e-103: 332: 18.72		ANR52_HUMAN (1-161): 1.16e-09: 57.8: 30.77