HitPredict

Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: CDN2D (P55273)
Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)
Gene: CDKN2D

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25275592
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation and 1 others more... GO:0032526 - response to retinoic acid
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 462 Hs			1 166
+	Hs
		533228 RARB_HUMAN (1-462): 6.2e-151: 438: 77.75		HACE1_HUMAN (2-97): 2.36e-20: 88.9: 24.74
+	Hs
		520606 RARA_HUMAN (1-424): 2.59e-148: 432: 100.00		HACE1_HUMAN (2-97): 2.36e-20: 88.9: 24.74
+	Hs
		396730 ESR1_HUMAN (5-460): 2.33e-119: 362: 21.81		EHMT2_HUMAN (11-164): 2.05e-42: 152: 23.27
+	Hs
		834033 HNF4A_HUMAN (61-462): 6.69e-120: 360: 24.52		EHMT2_HUMAN (11-164): 2.05e-42: 152: 23.27
+	Hs
		397197 ESR1_HUMAN (5-460): 2.33e-119: 362: 21.81		KDIS_HUMAN (2-142): 4.6e-36: 133: 23.29
+	Hs
		397101 ESR1_HUMAN (5-460): 2.33e-119: 362: 21.81		RAI14_HUMAN (5-142): 1.92e-34: 128: 25.18
+	Hs
		652481 NR4A1_HUMAN (16-420): 4.87e-105: 326: 30.50		CDN2D_HUMAN (1-166): 9.07e-52: 164: 100.00
+	Hs
		848097 NR4A2_HUMAN (10-420): 1.25e-102: 320: 29.33		CDN2D_HUMAN (1-166): 9.07e-52: 164: 100.00
+	Hs
		98528 F1D8N6_HUMAN (10-420): 1.25e-102: 320: 29.33		CDN2D_HUMAN (1-166): 9.07e-52: 164: 100.00
+	Hs
		295465 HNF4A_HUMAN (61-462): 6.69e-120: 360: 24.52		PSD10_HUMAN (48-165): 4.07e-34: 121: 21.67
+	Hs
		1367039 ESR2_HUMAN (3-447): 3.54e-106: 327: 24.89		EHMT2_HUMAN (11-164): 2.05e-42: 152: 23.27
+	Hs
		565529 RARG_HUMAN (1-448): 9.35e-131: 387: 71.62		HACE1_HUMAN (2-97): 2.36e-20: 88.9: 24.74
+	Mm
		886251 HNF4A_MOUSE (61-459): 5.27e-117: 352: 24.70		PSD10_MOUSE (48-165): 4.19e-34: 121: 20.83
+	Hs
		396973 ESR1_HUMAN (5-460): 2.33e-119: 362: 21.81		EHMT1_HUMAN (2-120): 5.57e-28: 110: 20.83
+	Hs
		834057 HNF4A_HUMAN (61-462): 6.69e-120: 360: 24.52		EHMT1_HUMAN (2-120): 5.57e-28: 110: 20.83
+	Hs
		1367454 ESR2_HUMAN (3-447): 3.54e-106: 327: 24.89		RAI14_HUMAN (5-142): 1.92e-34: 128: 25.18
+	Hs
		1055666 ESR2_HUMAN (3-447): 3.54e-106: 327: 24.89		GABP1_HUMAN (42-164): 2.16e-34: 126: 29.84
+	Hs
		1347270 ESR2_HUMAN (3-447): 3.54e-106: 327: 24.89		GABP2_HUMAN (42-164): 9.41e-34: 124: 29.84
+	Hs
		1295516 ESR2_HUMAN (3-447): 3.54e-106: 327: 24.89		MIB1_HUMAN (4-114): 1.06e-17: 80.9: 20.92
+	Mm
		1204119 ERR2_MOUSE (5-417): 5.89e-110: 333: 27.05		EHMT1_MOUSE (2-90): 3.17e-14: 71.2: 16.67