HitPredict

Interactor 1: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38943005
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 2752
+	Hs
		1462370 PPIE_HUMAN (2-163): 2.09e-88: 262: 67.28		SRRM2_HUMAN (1-2752): 2.19e-171: 594: 100.00
+	Hs
		986348 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		ANK2_HUMAN (891-2752): 1.07e-73: 278: 9.65
+	Hs
		590249 PPIF_HUMAN (3-164): 6.29e-92: 267: 76.54		MUC1_HUMAN (1729-2752): 1.62e-47: 190: 14.56
+	Hs
		986785 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		STAR9_HUMAN (764-2750): 5.65e-41: 170: 13.60
+	Hs
		986336 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		MAP1A_HUMAN (215-2617): 1.46e-38: 162: 9.07
+	Hs
		986598 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		TITIN_HUMAN (806-2717): 2.01e-34: 148: 6.33
+	Hs
		986429 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		NCOA6_HUMAN (821-2627): 3.07e-31: 137: 8.60
+	Hs
		1130609 PPIE_HUMAN (2-163): 2.09e-88: 262: 67.28		NCOA6_HUMAN (821-2627): 3.07e-31: 137: 8.60
+	Hs
		986651 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		CIC_HUMAN (21-2517): 2.53e-30: 134: 9.80
+	Hs
		890567 RBP2_HUMAN (3-164): 1.88e-73: 240: 66.67		CIC_HUMAN (21-2517): 2.53e-30: 134: 9.80
+	Hs
		656156 PPIB_HUMAN (2-165): 9.5e-88: 257: 63.64		NIPBL_HUMAN (333-1474): 1.71e-16: 89.1: 14.39
+	Hs
		161445 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		KMT2D_HUMAN (348-1707): 1.12e-10: 70.1: 8.21