Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1
Interactor 2: CHIO (P52757)
Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3)
Gene: CHN2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.77 | 1.00 | 0.879 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 32203420, unassigned1304, unassigned2213 |
| Identification Methods | two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~SH2, SH2~SH2, RhoGAP~SH3_1, SH2~SH3_1 |
| Common GO terms | GO:0005829 - cytosol |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
