HitPredict

Interactor 1: RL18 (Q07020)
Large ribosomal subunit protein eL18 (60S ribosomal protein L18)
Gene: RPL18

Interactor 2: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 353
+	Hs
		989952 RL18_HUMAN (1-188): 6.08e-96: 278: 100.00		RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83
+	Sc
		481636 RL18B_YEAST (1-187): 2.65e-76: 228: 55.32		RPF1_YEAST (4-269): 5.6e-62: 201: 15.33
+	Hs
		989950 RL18_HUMAN (1-188): 6.08e-96: 278: 100.00		RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88
+	Hs
		989959 RL18_HUMAN (1-188): 6.08e-96: 278: 100.00		SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22
+	Sc
		481574 RL18A_YEAST (1-187): 2.65e-76: 228: 55.32		RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56
+	Sc
		481621 RL18B_YEAST (1-187): 2.65e-76: 228: 55.32		RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56