HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: LCP2 (Q13094)
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)
Gene: LCP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	20936779, 17353368
Identification Methods	two hybrid, coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 533
+	Hs
		971466 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		LCP2_HUMAN (1-533): 2.39e-78: 257: 100.00
+	Mm
		989968 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		LCP2_MOUSE (1-531): 1.4e-72: 242: 80.98
+	Mm
		972226 1433E_MOUSE (2-241): 9.95e-144: 403: 68.18		LCP2_MOUSE (1-531): 1.4e-72: 242: 80.98
+	Mm
		996613 1433T_MOUSE (1-245): 9.02e-140: 393: 79.18		LCP2_MOUSE (1-531): 1.4e-72: 242: 80.98
+	Mm
		236366 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		O54737_MOUSE (52-523): 4.08e-31: 128: 19.92
+	Hs
		971632 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		TENS2_HUMAN (76-512): 1.92e-30: 128: 17.42
+	Hs
		319061 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (16-378): 3.91e-29: 125: 11.84
+	Hs
		319058 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		K0754_HUMAN (16-378): 3.91e-29: 125: 11.84
+	Hs
		691114 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		TENS2_HUMAN (76-512): 1.92e-30: 128: 17.42
+	Hs
		691117 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		TENS3_HUMAN (83-512): 2.88e-29: 125: 12.50
+	Hs
		990757 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TENS1_HUMAN (85-512): 6.08e-23: 105: 14.61
+	Hs
		691449 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		TENS1_HUMAN (85-512): 6.08e-23: 105: 14.61
+	Hs
		990385 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		OTOG_HUMAN (34-473): 9.26e-16: 83.1: 12.78
+	Hs
		971678 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		OTOG_HUMAN (34-473): 9.26e-16: 83.1: 12.78
+	Hs
		691153 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		OTOG_HUMAN (34-473): 9.26e-16: 83.1: 12.78
+	Hs
		990550 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TITIN_HUMAN (65-384): 2.15e-11: 69.3: 12.27
+	Hs
		176258 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		SYNJ2_HUMAN (125-443): 2.57e-09: 62.3: 11.77
+	Hs
		691291 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		TITIN_HUMAN (65-384): 2.15e-11: 69.3: 12.27
+	Hs
		176247 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		SYNJ2_HUMAN (125-443): 2.57e-09: 62.3: 11.77
+	Hs
		691588 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		CABIN_HUMAN (232-471): 2.36e-09: 62.3: 10.12