HitPredict

Interactor 1: ACTG (P63260)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: Actg1

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22496869
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Mm			1 336
+	Mm
		1295885 ACTBL_MOUSE (1-375): 0: 741: 92.27		RING2_MOUSE (1-336): 1.6e-106: 316: 100.00
+	Mm
		953287 ACTB_MOUSE (1-375): 0: 604: 98.93		RING2_MOUSE (1-336): 1.6e-106: 316: 100.00
+	Hs
		993302 ACTG_HUMAN (1-375): 0: 604: 100.00		RING2_HUMAN (1-336): 2.07e-106: 316: 99.70
+	Hs
		765635 POTEE_HUMAN (1-375): 0: 729: 91.47		BMI1_HUMAN (34-332): 8.46e-43: 152: 16.83
+	Hs
		623371 ACTBL_HUMAN (2-375): 0: 734: 91.44		RO52_HUMAN (36-249): 1.93e-36: 138: 13.08
+	Hs
		765360 ACTG_HUMAN (1-375): 0: 604: 100.00		BMI1_HUMAN (34-332): 8.46e-43: 152: 16.83
+	Hs
		765333 ACTA_HUMAN (2-375): 0: 594: 94.39		BMI1_HUMAN (34-332): 8.46e-43: 152: 16.83
+	Hs
		623217 ACTB_HUMAN (1-375): 0: 604: 98.93		RO52_HUMAN (36-249): 1.93e-36: 138: 13.08
+	Hs
		623263 ACTG_HUMAN (1-375): 0: 604: 100.00		RO52_HUMAN (36-249): 1.93e-36: 138: 13.08
+	Hs
		952786 ACTB_HUMAN (1-375): 0: 604: 98.93		TRI26_HUMAN (36-283): 2.26e-35: 136: 17.05
+	Hs
		798970 ACTG_HUMAN (1-375): 0: 604: 100.00		BRCA1_HUMAN (36-213): 1.89e-33: 132: 25.93
+	Hs
		995804 ACTC_HUMAN (2-375): 0: 594: 94.39		TRI55_HUMAN (42-318): 3.35e-37: 141: 13.42
+	Hs
		996529 ACTS_HUMAN (2-375): 0: 594: 93.85		TRI55_HUMAN (42-318): 3.35e-37: 141: 13.42
+	Hs
		623244 ACTA_HUMAN (2-375): 0: 594: 94.39		RO52_HUMAN (36-249): 1.93e-36: 138: 13.08
+	Hs
		623266 ACTS_HUMAN (2-375): 0: 594: 93.85		RO52_HUMAN (36-249): 1.93e-36: 138: 13.08
+	Hs
		953083 ACTB_HUMAN (1-375): 0: 604: 98.93		TRIM6_HUMAN (38-292): 1.1e-31: 125: 13.28
+	Hs
		996531 ACTS_HUMAN (2-375): 0: 594: 93.85		TRIM6_HUMAN (38-292): 1.1e-31: 125: 13.28
+	Hs
		993443 ACTH_HUMAN (2-375): 0: 592: 94.39		TRIM6_HUMAN (38-292): 1.1e-31: 125: 13.28
+	Mm
		993113 ACTG_MOUSE (1-375): 0: 604: 100.00		RN138_MOUSE (34-233): 5.38e-28: 110: 18.00
+	Mm
		995937 ACTC_MOUSE (2-375): 0: 594: 94.39		RN138_MOUSE (34-233): 5.38e-28: 110: 18.00