Protein: DPPA4
Developmental pluripotency-associated protein 4

Gene: DPPA4
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q7L190

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0048731 - system development
GO:0060484 - lung-associated mesenchyme development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1271210

SH3G1
Endophilin-A2

10

4

High-throughput

0.691

High

343772

LDOC1
Protein LDOC1

4

0

High-throughput

0.675

High

774082

ADDA
Alpha-adducin

3

1

High-throughput

0.667

High

1247600

SAMD1
Sterile alpha motif domain-containing protein 1

3

2

High-throughput

0.667

High

1271202

LMBL3
Lethal(3)malignant brain tumor-like protein 3

3

1

High-throughput

0.667

High

1198301

TIGD5
Tigger transposable element-derived protein 5

3

0

High-throughput

0.638

High

855663

CRK
Adapter molecule crk

2

2

High-throughput

0.632

High

1271178

DPPA2
Developmental pluripotency-associated protein 2

2

2

High-throughput

0.614

High

276596

LX12B
Arachidonate 12-lipoxygenase, 12R-type

3

1

High-throughput

0.609

High

774156

ADDB
Beta-adducin

3

3

High-throughput

0.609

High

1271218

LOXE3
Hydroperoxide isomerase ALOXE3

3

1

High-throughput

0.609

High

1271237

SNX9
Sorting nexin-9

3

2

High-throughput

0.609

High

1111768

GRAP
GRB2-related adapter protein

2

1

High-throughput

0.606

High

1127353

CASL
Enhancer of filamentation 1

2

2

High-throughput

0.606

High

961053

MGN
Protein mago nashi homolog

2

0

High-throughput

0.580

High

1137810

TNIP1
TNFAIP3-interacting protein 1

2

0

High-throughput

0.580

High

1244922

FOXR1
Forkhead box protein R1

2

0

High-throughput

0.580

High

1271182

CIR1
Corepressor interacting with RBPJ 1

2

0

High-throughput

0.580

High

1271197

GTPB3
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial

2

0

High-throughput

0.580

High

1271201

EAF1
ELL-associated factor 1

2

0

High-throughput

0.580

High

1271219

IN80B
INO80 complex subunit B

2

0

High-throughput

0.580

High

1271226

CSR2B
Cysteine-rich protein 2-binding protein

2

0

High-throughput

0.580

High

1271233

TLK1
Serine/threonine-protein kinase tousled-like 1

2

0

High-throughput

0.580

High

987732

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.573

High

1271192

SNX33
Sorting nexin-33

2

3

High-throughput

0.553

High

1271205

SNX18
Sorting nexin-18

2

2

High-throughput

0.553

High

635608

FILA
Filaggrin

1

1

High-throughput

0.536

High

713401

SPB3
Serpin B3

1

1

High-throughput

0.536

High

1271199

S10AG
Protein S100-A16

1

2

High-throughput

0.536

High

1271216

PCGF1
Polycomb group RING finger protein 1

1

2

High-throughput

0.536

High

843701

HD
Huntingtin

1

0

High-throughput

0.518

High

894850

EMD
Emerin

1

0

High-throughput

0.518

High

156299

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.513

High

1271208

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.513

High

1271213

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.513

High

1271222

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

1271212

SH3G3
Endophilin-A3

1

4

High-throughput

0.494

High

457875

INVO
Involucrin

1

4

High-throughput

0.489

High

874804

SPB4
Serpin B4

1

1

High-throughput

0.489

High

1271180

S1A7A
Protein S100-A7A

1

2

High-throughput

0.489

High

658611

KS6B1
Ribosomal protein S6 kinase beta-1

1

0

High-throughput

0.486

High

1161123

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.486

High

163792

TCRG1
Transcription elongation regulator 1

1

2

High-throughput

0.479

High

325908

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

High-throughput

0.479

High

851597

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

907649

ZN157
Zinc finger protein 157

1

1

High-throughput

0.479

High

1088888

TP53B
TP53-binding protein 1

1

4

High-throughput

0.479

High

1129636

MDC1
Mediator of DNA damage checkpoint protein 1

1

3

High-throughput

0.479

High

1257905

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

1

High-throughput

0.479

High

1271176

DPPA4
Developmental pluripotency-associated protein 4

1

2

High-throughput

0.479

High

1271187

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.479

High

1271190

SMRC2
SWI/SNF complex subunit SMARCC2

1

2

High-throughput

0.479

High

1271196

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

1

High-throughput

0.479

High

1271200

SPF45
Splicing factor 45

1

1

High-throughput

0.479

High

1271207

MINT
Msx2-interacting protein

1

3

High-throughput

0.479

High

1271209

SCAFB
Protein SCAF11

1

3

High-throughput

0.479

High

1271215

GCP2
Gamma-tubulin complex component 2

1

1

High-throughput

0.479

High

1271221

NAA50
N-alpha-acetyltransferase 50

1

1

High-throughput

0.479

High

1271231

IBTK
Inhibitor of Bruton tyrosine kinase

1

1

High-throughput

0.479

High

1232345

Q6FGM0
Endophilin-A2

1

4

High-throughput

0.470

High

1271211

SH3G2
Endophilin-A1

1

5

High-throughput

0.464

High

144283

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.458

High

258464

EDF1
Endothelial differentiation-related factor 1

1

0

High-throughput

0.458

High

262092

NBN
Nibrin

1

0

High-throughput

0.458

High

528283

THIO
Thioredoxin

1

0

High-throughput

0.458

High

533702

CLUS
Clusterin

1

0

High-throughput

0.458

High

601746

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.458

High

623405

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

721024

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.458

High

726775

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

0

High-throughput

0.458

High

888151

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

913524

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.458

High

1033711

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1098356

ERCC8
DNA excision repair protein ERCC-8

1

0

High-throughput

0.458

High

1114912

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1116513

FHL3
Four and a half LIM domains protein 3

1

0

High-throughput

0.458

High

1117104

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

1128417

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

0

High-throughput

0.458

High

1137363

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1147060

ELOC
Elongin-C

1

0

High-throughput

0.458

High

1151000

PCH2
Pachytene checkpoint protein 2 homolog

1

0

High-throughput

0.458

High

1157781

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.458

High

1208043

CYTSB
Cytospin-B

1

0

High-throughput

0.458

High

1239856

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

1241147

LTMD1
LETM1 domain-containing protein 1

1

0

High-throughput

0.458

High

1271177

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1271179

ZN467
Zinc finger protein 467

1

0

High-throughput

0.458

High

1271181

PB1
Protein polybromo-1

1

0

High-throughput

0.458

High

1271185

CDAN1
Codanin-1

1

0

High-throughput

0.458

High

1271186

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.458

High

1271191

GAR3
Golgi-associated RAB2 interactor protein 3

1

0

High-throughput

0.458

High

1271195

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.458

High

1271206

CRBN
Protein cereblon

1

0

High-throughput

0.458

High

1271228

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

0

High-throughput

0.458

High

1271234

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.458

High

1271235

ING4
Inhibitor of growth protein 4

1

0

High-throughput

0.458

High

1271220

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

1

High-throughput

0.457

High

1271224

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

1

High-throughput

0.457

High

1271194

OSTF1
Osteoclast-stimulating factor 1

1

2

High-throughput

0.439

High

405609

HRG
Histidine-rich glycoprotein

1

2

High-throughput

0.437

High

643507

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.437

High

1271198

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.437

High

1271204

PRAM
PML-RARA-regulated adapter molecule 1

1

3

High-throughput

0.437

High

1271229

PCMD2
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

1

1

High-throughput

0.437

High

1271232

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

2

High-throughput

0.437

High

1271238

PCLO
Protein piccolo

1

1

High-throughput

0.437

High

423796

APOD
Apolipoprotein D

3

0

High-throughput

0.347

High

652339

TGM1
Protein-glutamine gamma-glutamyltransferase K

3

0

High-throughput

0.347

High

839574

HUTH
Histidine ammonia-lyase

3

0

High-throughput

0.347

High

1271189

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

3

0

High-throughput

0.347

High

1208298

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

2

0

High-throughput

0.316

High

1271184

MISP
Mitotic interactor and substrate of PLK1

2

0

High-throughput

0.316

High

1271236

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

2

0

High-throughput

0.316

High

1124267

IF4A2
Eukaryotic initiation factor 4A-II

1

0

High-throughput

0.299

High

1271203

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

0

High-throughput

0.299

High

474774

VIME
Vimentin

1

0

High-throughput

0.282

High

248729

PEPL
Periplakin

1

0

High-throughput

0.279

Low

1159390

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1186209

CEA21
Cell adhesion molecule CEACAM21

1

0

High-throughput

0.279

Low

1256950

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

1271193

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1271223

RNAS7
Ribonuclease 7

1

0

High-throughput

0.279

Low

1271230

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.279

Low

868195

SYQ
Glutamine--tRNA ligase

1

0

High-throughput

0.265

Low

1163780

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.265

Low

1271217

BTBD2
BTB/POZ domain-containing protein 2

1

0

High-throughput

0.265

Low

1271227

PKHF2
Pleckstrin homology domain-containing family F member 2

1

0

High-throughput

0.265

Low

301095

RL1D1
Ribosomal L1 domain-containing protein 1

1

0

High-throughput

0.249

Low

581551

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

0

High-throughput

0.249

Low

597328

PDE6A
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

1

0

High-throughput

0.249

Low

641619

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

0

High-throughput

0.249

Low

857135

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.249

Low

902202

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.249

Low

1105697

HAP28
28 kDa heat- and acid-stable phosphoprotein

1

0

High-throughput

0.249

Low

1219388

S31G1
Spermatogenesis-associated protein 31G1

1

0

High-throughput

0.249

Low

1248137

SAS6
Spindle assembly abnormal protein 6 homolog

1

0

High-throughput

0.249

Low

1271183

TMTC1
Protein O-mannosyl-transferase TMTC1

1

0

High-throughput

0.249

Low

1271188

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

0

High-throughput

0.249

Low

1271214

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.249

Low

1271225

TOR3A
Torsin-3A

1

0

High-throughput

0.249

Low

1214152

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025