HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9535861
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 147
+	Hs
		587492 NFKB1_HUMAN (1-968): 0: 796: 100.00		UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28
+	Hs
		849310 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12
+	Hs
		919709 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00
+	Hs
		895779 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28
+	Hs
		981791 REL_HUMAN (35-484): 6.21e-110: 354: 33.91		UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20
+	Hs
		851805 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		UB2E1_HUMAN (4-146): 8.81e-73: 217: 65.73
+	Hs
		639701 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12
+	Hs
		639719 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00
+	Hs
		639710 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28
+	Hs
		883463 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22
+	Hs
		1206094 MIB1_HUMAN (478-689): 3.14e-30: 131: 23.11		UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20
+	Hs
		849363 MIB1_HUMAN (478-689): 3.14e-30: 131: 23.11		UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12
+	Hs
		919776 MIB1_HUMAN (478-689): 3.14e-30: 131: 23.11		UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00
+	Hs
		895841 MIB1_HUMAN (478-689): 3.14e-30: 131: 23.11		UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28
+	Hs
		896486 MIB1_HUMAN (478-689): 3.14e-30: 131: 23.11		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22
+	Hs
		829062 Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41		UBE2A_HUMAN (2-144): 1.41e-70: 210: 39.16
+	Hs
		896542 Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22