Protein: NCPR
NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)

Gene: NCPR, POR
Organism: Homo sapiens
Interactions: 146
UniProt ID: P16435

Gene Ontology (top 5):
GO:0003958 - NADPH-hemoprotein reductase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006805 - xenobiotic metabolic process
GO:0009725 - response to hormone

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

514663

CP2C9
Cytochrome P450 2C9

3

6

Small-scale

0.840

High

398437

CP2E1
Cytochrome P450 2E1

3

6

Small-scale

0.840

High

398427

CP1A2
Cytochrome P450 1A2

2

7

Small-scale

0.778

High

560163

CP2CJ
Cytochrome P450 2C19

2

6

Small-scale

0.778

High

560238

UBXN6
UBX domain-containing protein 6

4

1

High-throughput

0.694

High

560180

SC61B
Protein transport protein Sec61 subunit beta

3

1

High-throughput

0.656

High

443995

CP3A4
Cytochrome P450 3A4

1

4

Small-scale

0.647

High

496154

CP2D6
Cytochrome P450 2D6

1

7

Small-scale

0.647

High

513728

CP2A6
Cytochrome P450 2A6

1

6

Small-scale

0.647

High

123486

PGRC1
Membrane-associated progesterone receptor component 1

2

3

Small-scale

0.635

High

560154

NCPR
NADPH--cytochrome P450 reductase

1

10

Small-scale

0.621

High

390056

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

1

High-throughput

0.611

High

390702

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

1

High-throughput

0.611

High

560175

BAP31
B-cell receptor-associated protein 31

2

1

High-throughput

0.611

High

560236

DERL1
Derlin-1

2

2

High-throughput

0.611

High

560178

SYRC
Arginine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

560263

SNX8
Sorting nexin-8

2

0

High-throughput

0.602

High

560204

EMC4
ER membrane protein complex subunit 4

2

0

High-throughput

0.585

High

560190

FANCC
Fanconi anemia group C protein

1

1

Small-scale

0.581

High

560161

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

170789

PGRC2
Membrane-associated progesterone receptor component 2

1

3

High-throughput

0.536

High

446006

CD63
CD63 antigen

1

3

High-throughput

0.536

High

560198

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.536

High

560199

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.536

High

560213

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

High-throughput

0.536

High

560229

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

560237

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.536

High

560241

DERL2
Derlin-2

1

2

High-throughput

0.536

High

560247

RTN4
Reticulon-4

1

3

High-throughput

0.536

High

560254

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.536

High

560176

CAV2
Caveolin-2

2

4

High-throughput

0.521

High

560242

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.515

High

254546

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.513

High

438682

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.513

High

473091

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.513

High

560160

CALX
Calnexin

1

0

High-throughput

0.513

High

560164

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

560171

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

560185

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

560223

F241A
Uncharacterized protein FAM241A

1

0

High-throughput

0.513

High

560226

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.513

High

560211

RABEK
Rab9 effector protein with kelch motifs

1

5

High-throughput

0.508

High

560189

CYC
Cytochrome c

1

1

Small-scale

0.501

High

560162

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

560167

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

3

High-throughput

0.481

High

48256

ESYT2
Extended synaptotagmin-2

1

3

High-throughput

0.479

High

120297

RHOD
Rho-related GTP-binding protein RhoD

1

16

High-throughput

0.479

High

163738

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

4

High-throughput

0.479

High

167833

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

226444

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

315178

CNEP1
CTD nuclear envelope phosphatase 1

1

1

High-throughput

0.479

High

348497

RASN
GTPase NRas

1

2

High-throughput

0.479

High

349854

RASK
GTPase KRas

1

1

High-throughput

0.479

High

377072

GCR
Glucocorticoid receptor

1

4

Small-scale

0.479

High

397761

ISG15
Ubiquitin-like protein ISG15

1

3

High-throughput

0.479

High

436146

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.479

High

545195

RAC2
Ras-related C3 botulinum toxin substrate 2

1

14

High-throughput

0.479

High

560155

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

560158

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

560166

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

560168

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.479

High

560169

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

2

Small-scale

0.479

High

560172

EMD
Emerin

1

2

High-throughput

0.479

High

560173

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

560174

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

560177

RND2
Rho-related GTP-binding protein RhoN

1

15

High-throughput

0.479

High

560179

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

560181

RAC3
Ras-related C3 botulinum toxin substrate 3

1

14

High-throughput

0.479

High

560182

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

560184

RHOA
Transforming protein RhoA

1

15

High-throughput

0.479

High

560186

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.479

High

560188

RHOG
Rho-related GTP-binding protein RhoG

1

14

High-throughput

0.479

High

560192

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

560193

CKAP4
Cytoskeleton-associated protein 4

1

3

High-throughput

0.479

High

560196

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.479

High

560197

CUL3
Cullin-3

1

1

High-throughput

0.479

High

560201

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

560215

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

560218

GOLI
E3 ubiquitin-protein ligase RNF130

1

3

High-throughput

0.479

High

560224

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

560225

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.479

High

560230

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

560231

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

560234

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

560235

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.479

High

560240

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.479

High

560244

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

560246

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

560250

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.479

High

560251

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.479

High

560256

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

560257

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

560258

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

560259

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

148365

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

155263

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

181052

INSI1
Insulin-induced gene 1 protein

1

0

Small-scale

0.458

High

209647

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

560165

ARL1
ADP-ribosylation factor-like protein 1

1

0

High-throughput

0.458

High

560170

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

560194

STX4
Syntaxin-4

1

0

High-throughput

0.458

High

560195

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

560200

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.458

High

560203

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

560205

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

560207

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

560217

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

560222

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

560227

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.458

High

560243

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

560245

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

560248

ANLN
Anillin

1

0

High-throughput

0.458

High

560249

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

560253

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

560255

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

560262

SRPRB
Signal recognition particle receptor subunit beta

1

0

High-throughput

0.458

High

523500

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.457

High

100452

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

214076

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.437

High

384216

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

560156

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

560187

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

560202

RHOH
Rho-related GTP-binding protein RhoH

1

15

High-throughput

0.437

High

560206

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

560208

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

560210

BT2A1
Butyrophilin subfamily 2 member A1

1

4

High-throughput

0.437

High

560212

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.437

High

560228

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

560233

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

560252

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

496236

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

560239

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

560159

MATN1
Cartilage matrix protein

1

0

High-throughput

0.279

Low

560183

FGF12
Fibroblast growth factor 12

1

0

High-throughput

0.279

Low

560221

KTAP2
Keratinocyte-associated protein 2

1

0

High-throughput

0.279

Low

560232

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

560260

NTNG1
Netrin-G1

1

0

High-throughput

0.279

Low

560261

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

560157

RAB4A
Ras-related protein Rab-4A

1

0

High-throughput

0.249

Low

560191

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

560209

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

560214

LBN
Limbin

1

0

High-throughput

0.249

Low

560216

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

560219

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

560220

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024