Protein: IFT74
Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2)

Gene: IFT74
Organism: Homo sapiens
Interactions: 131
UniProt ID: Q96LB3

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0003334 - keratinocyte development
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1361470

IFT81
Intraflagellar transport protein 81 homolog

7

20

High-throughput

0.747

High

1396974

IFT57
Intraflagellar transport protein 57 homolog

5

1

High-throughput

0.716

High

1292708

IT70A
Intraflagellar transport protein 70A

4

1

High-throughput

0.697

High

1326661

IT70B
Intraflagellar transport protein 70B

4

1

High-throughput

0.697

High

1187534

AR13B
ADP-ribosylation factor-like protein 13B

4

9

High-throughput

0.691

High

1396970

IFT22
Intraflagellar transport protein 22 homolog

3

8

High-throughput

0.675

High

63313

ODAD3
Outer dynein arm-docking complex subunit 3

3

19

High-throughput

0.667

High

1181268

LRRF1
Leucine-rich repeat flightless-interacting protein 1

3

3

High-throughput

0.662

High

1396973

DISC1
Disrupted in schizophrenia 1 protein

3

7

High-throughput

0.650

High

1396972

IFT46
Intraflagellar transport protein 46 homolog

3

0

High-throughput

0.646

High

1396989

IFT52
Intraflagellar transport protein 52 homolog

3

0

High-throughput

0.646

High

1396965

IFT27
Intraflagellar transport protein 27 homolog

2

16

High-throughput

0.635

High

1396990

SKAP
Small kinetochore-associated protein

3

0

High-throughput

0.634

High

1186129

ANR55
Ankyrin repeat domain-containing protein 55

4

13

High-throughput

0.633

High

1392324

BORC6
BLOC-1-related complex subunit 6

4

1

High-throughput

0.633

High

1396981

TSYL4
Testis-specific Y-encoded-like protein 4

2

4

High-throughput

0.628

High

1396991

IFT25
Intraflagellar transport protein 25 homolog

2

0

High-throughput

0.608

High

1379994

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

4

High-throughput

0.606

High

246868

KDM1A
Lysine-specific histone demethylase 1A

2

7

High-throughput

0.584

High

1143478

PCM1
Pericentriolar material 1 protein

2

2

High-throughput

0.584

High

1226225

CP135
Centrosomal protein of 135 kDa

2

17

High-throughput

0.584

High

1396988

NINL
Ninein-like protein

2

19

High-throughput

0.584

High

821183

TXLNA
Alpha-taxilin

2

19

High-throughput

0.574

High

935440

FGF8
Fibroblast growth factor 8

2

3

High-throughput

0.574

High

1350262

RHPN1
Rhophilin-1

2

6

High-throughput

0.574

High

1395068

JPH4
Junctophilin-4

2

1

High-throughput

0.574

High

1396986

SIGL7
Sialic acid-binding Ig-like lectin 7

2

8

High-throughput

0.574

High

1291344

LCA5
Lebercilin

2

20

High-throughput

0.571

High

1094471

IFT88
Intraflagellar transport protein 88 homolog

1

7

High-throughput

0.565

High

1396979

IF172
Intraflagellar transport protein 172 homolog

1

12

High-throughput

0.554

High

169709

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

5

High-throughput

0.553

High

1396963

KXDL1
KxDL motif-containing protein 1

2

4

High-throughput

0.549

High

1396958

UBX10
UBX domain-containing protein 10

1

0

High-throughput

0.537

High

262424

DTNB
Dystrobrevin beta

1

6

High-throughput

0.536

High

1396959

ODAD1
Outer dynein arm-docking complex subunit 1

1

19

High-throughput

0.536

High

466699

GLI1
Zinc finger protein GLI1

1

5

High-throughput

0.536

High

1275616

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

9

High-throughput

0.536

High

1351557

GNPI2
Glucosamine-6-phosphate deaminase 2

1

1

High-throughput

0.536

High

1351576

MIPT3
TRAF3-interacting protein 1

1

6

High-throughput

0.536

High

1396977

IFT80
Intraflagellar transport protein 80 homolog

1

16

High-throughput

0.536

High

1163145

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.515

High

48169

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.513

High

593188

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

1293469

NIT1
Deaminated glutathione amidase

1

0

High-throughput

0.513

High

1313682

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.513

High

1154157

ITSN1
Intersectin-1

1

16

High-throughput

0.494

High

49575

FEZF1
Fez family zinc finger protein 1

1

4

High-throughput

0.489

High

424542

PAI2
Plasminogen activator inhibitor 2

1

2

High-throughput

0.489

High

871179

TFPI2
Tissue factor pathway inhibitor 2

1

3

High-throughput

0.489

High

1331599

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

13

High-throughput

0.489

High

164055

NDC80
Kinetochore protein NDC80 homolog

1

19

High-throughput

0.479

High

190161

TNC18
Trinucleotide repeat-containing gene 18 protein

1

9

High-throughput

0.479

High

242614

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.479

High

256955

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.479

High

278938

PEX14
Peroxisomal membrane protein PEX14

1

2

High-throughput

0.479

High

279465

TULP3
Tubby-related protein 3

1

5

High-throughput

0.479

High

290111

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

315897

RECQ4
ATP-dependent DNA helicase Q4

1

14

High-throughput

0.479

High

437304

K2C8
Keratin, type II cytoskeletal 8

1

5

High-throughput

0.479

High

459720

PROF1
Profilin-1

1

4

High-throughput

0.479

High

475663

K1C19
Keratin, type I cytoskeletal 19

1

11

High-throughput

0.479

High

589438

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

696245

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

791637

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

876121

TCPE
T-complex protein 1 subunit epsilon

1

10

High-throughput

0.479

High

935014

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.479

High

981020

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

1051039

FAK1
Focal adhesion kinase 1

1

20

High-throughput

0.479

High

1096791

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

1108048

SQSTM
Sequestosome-1

1

9

High-throughput

0.479

High

1109994

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.479

High

1110690

DCTN2
Dynactin subunit 2

1

2

High-throughput

0.479

High

1123766

DCTN1
Dynactin subunit 1

1

18

High-throughput

0.479

High

1203229

ODFP2
Outer dense fiber protein 2

1

19

High-throughput

0.479

High

1210955

CE170
Centrosomal protein of 170 kDa

1

15

High-throughput

0.479

High

1215492

CE162
Centrosomal protein of 162 kDa

1

19

High-throughput

0.479

High

1219876

OBI1
ORC ubiquitin ligase 1

1

1

High-throughput

0.479

High

1228454

FTM
Protein fantom

1

20

High-throughput

0.479

High

1256561

CE128
Centrosomal protein of 128 kDa

1

19

High-throughput

0.479

High

1295534

MIB1
E3 ubiquitin-protein ligase MIB1

1

8

High-throughput

0.479

High

1326310

NIN
Ninein

1

20

High-throughput

0.479

High

1353123

FBF1
Fas-binding factor 1

1

19

High-throughput

0.479

High

1368934

GOGA1
Golgin subfamily A member 1

1

17

High-throughput

0.479

High

1384408

PF21A
PHD finger protein 21A

1

15

High-throughput

0.479

High

1391160

BICD1
Protein bicaudal D homolog 1

1

18

High-throughput

0.479

High

1396179

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

19

High-throughput

0.479

High

1396960

CEP63
Centrosomal protein of 63 kDa

1

19

High-throughput

0.479

High

1396962

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.479

High

1396966

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

6

High-throughput

0.479

High

1396967

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.479

High

1396971

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

High-throughput

0.479

High

1396976

SEP10
Septin-10

1

4

High-throughput

0.479

High

1396978

ZO2
Tight junction protein 2

1

4

High-throughput

0.479

High

1396980

SEPT9
Septin-9

1

8

High-throughput

0.479

High

1396982

HOOK1
Protein Hook homolog 1

1

19

High-throughput

0.479

High

1396984

RCOR1
REST corepressor 1

1

7

High-throughput

0.479

High

1396987

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.479

High

1347634

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.458

High

1369976

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.458

High

1383228

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1396964

CC28B
Coiled-coil domain-containing protein 28B

1

0

High-throughput

0.458

High

1396969

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1396975

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

584134

FOSL2
Fos-related antigen 2

1

6

High-throughput

0.445

High

436971

K1C18
Keratin, type I cytoskeletal 18

1

14

High-throughput

0.437

High

474904

VIME
Vimentin

1

20

High-throughput

0.437

High

582925

EZRI
Ezrin

1

14

High-throughput

0.437

High

833343

PERI
Peripherin

1

20

High-throughput

0.437

High

878539

PAXI
Paxillin

1

14

High-throughput

0.437

High

896612

VASP
Vasodilator-stimulated phosphoprotein

1

4

High-throughput

0.437

High

1049669

1433F
14-3-3 protein eta

1

20

High-throughput

0.437

High

1141868

EEA1
Early endosome antigen 1

1

20

High-throughput

0.437

High

1156579

CCDC6
Coiled-coil domain-containing protein 6

1

19

High-throughput

0.437

High

1197059

AMOT
Angiomotin

1

20

High-throughput

0.437

High

1249126

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1252183

SYNE3
Nesprin-3

1

20

High-throughput

0.437

High

1255112

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1338906

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.437

High

1383390

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

2

High-throughput

0.437

High

1396968

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1396983

ANC2
Anaphase-promoting complex subunit 2

1

18

High-throughput

0.437

High

1396985

MARE3
Microtubule-associated protein RP/EB family member 3

1

2

High-throughput

0.437

High

244997

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

1396961

MTMR9
Myotubularin-related protein 9

1

3

High-throughput

0.407

High

1179840

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1198839

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

0

High-throughput

0.279

Low

1322129

SYCE1
Synaptonemal complex central element protein 1

1

0

High-throughput

0.279

Low

1325075

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.279

Low

4795

A0A1B0GWI1
Coiled-coil domain containing 196

1

0

High-throughput

0.268

Low

1287049

K1328
Protein hinderin

1

0

High-throughput

0.268

Low

516119

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025