Protein: IFT57
Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2)

Gene: IFT57
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q9NWB7

Gene Ontology (top 5):
GO:0001843 - neural tube closure
GO:0001947 - heart looping
GO:0003677 - DNA binding
GO:0005794 - Golgi apparatus
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1313709

IFT20
Intraflagellar transport protein 20 homolog

7

1

High-throughput

0.965

High

1383260

CLUA1
Clusterin-associated protein 1

6

0

High-throughput

0.897

High

1351602

MIPT3
TRAF3-interacting protein 1

5

0

High-throughput

0.877

High

1094483

IFT88
Intraflagellar transport protein 88 homolog

5

1

High-throughput

0.720

High

1451180

IF172
Intraflagellar transport protein 172 homolog

5

1

High-throughput

0.718

High

1292715

IT70A
Intraflagellar transport protein 70A

5

1

High-throughput

0.716

High

1396974

IFT74
Intraflagellar transport protein 74 homolog

5

1

High-throughput

0.716

High

1451177

IFT80
Intraflagellar transport protein 80 homolog

5

2

High-throughput

0.716

High

1326672

IT70B
Intraflagellar transport protein 70B

5

1

High-throughput

0.712

High

1340680

NEDD1
Protein NEDD1

4

1

High-throughput

0.691

High

1451185

IFT52
Intraflagellar transport protein 52 homolog

4

1

High-throughput

0.691

High

1435937

IFT22
Intraflagellar transport protein 22 homolog

5

0

High-throughput

0.682

High

1447056

IFT46
Intraflagellar transport protein 46 homolog

5

0

High-throughput

0.682

High

48177

IFT56
Intraflagellar transport protein 56

4

0

High-throughput

0.661

High

1246168

TRAF7
E3 ubiquitin-protein ligase TRAF7

4

0

High-throughput

0.661

High

1334184

POC1A
POC1 centriolar protein homolog A

4

0

High-throughput

0.661

High

1350777

TRPM4
Transient receptor potential cation channel subfamily M member 4

4

0

High-throughput

0.661

High

1361489

IFT81
Intraflagellar transport protein 81 homolog

4

0

High-throughput

0.661

High

1401176

SPAG5
Sperm-associated antigen 5

4

0

High-throughput

0.661

High

1434688

RABE2
Rab GTPase-binding effector protein 2

4

0

High-throughput

0.661

High

1451183

EXOC7
Exocyst complex component 7

4

0

High-throughput

0.661

High

724430

COR1A
Coronin-1A

5

2

High-throughput

0.654

High

1091989

SEC20
Vesicle transport protein SEC20

3

0

High-throughput

0.638

High

1291592

HOOK3
Protein Hook homolog 3

3

0

High-throughput

0.638

High

1338585

SYNE1
Nesprin-1

3

0

High-throughput

0.638

High

1451186

SKAP
Small kinetochore-associated protein

3

0

High-throughput

0.638

High

1295220

HOME1
Homer protein homolog 1

4

2

High-throughput

0.630

High

1449318

HOME3
Homer protein homolog 3

4

2

High-throughput

0.630

High

1415972

IFT27
Intraflagellar transport protein 27 homolog

3

0

High-throughput

0.616

High

1449300

HOME2
Homer protein homolog 2

3

2

High-throughput

0.609

High

1143558

PCM1
Pericentriolar material 1 protein

3

0

High-throughput

0.606

High

935463

FGF8
Fibroblast growth factor 8

2

0

High-throughput

0.602

High

131024

HIP1
Huntingtin-interacting protein 1

2

0

Small-scale

0.593

High

1132451

CASP8
Caspase-8

2

2

Small-scale

0.584

High

137280

EXOC5
Exocyst complex component 5

2

0

High-throughput

0.580

High

1314061

YAF2
YY1-associated factor 2

2

0

High-throughput

0.580

High

1451188

IFT25
Intraflagellar transport protein 25 homolog

2

0

High-throughput

0.576

High

1411032

COR1B
Coronin-1B

2

2

High-throughput

0.558

High

1451181

PRP19
Pre-mRNA-processing factor 19

2

1

High-throughput

0.558

High

1307659

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.558

High

1246507

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

0

Small-scale

0.549

High

1291367

LCA5
Lebercilin

2

0

High-throughput

0.547

High

1408038

H2B1M
Histone H2B type 1-M

1

0

High-throughput

0.493

High

844031

HD
Huntingtin

1

0

High-throughput

0.493

High

1235631

K2C80
Keratin, type II cytoskeletal 80

1

1

High-throughput

0.489

High

1397083

UBX10
UBX domain-containing protein 10

1

0

High-throughput

0.480

High

712894

CASP1
Caspase-1

1

2

Small-scale

0.479

High

1227565

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1369559

CASPA
Caspase-10

1

2

Small-scale

0.479

High

164113

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.458

High

257183

CCD22
Coiled-coil domain-containing protein 22

1

0

High-throughput

0.458

High

290175

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

675181

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

1110743

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1193485

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

1256612

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.458

High

1325623

TXND3
Thioredoxin domain-containing protein 3

1

0

High-throughput

0.458

High

1399106

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.458

High

1431549

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.458

High

1451175

BFAR
Bifunctional apoptosis regulator

1

0

Small-scale

0.458

High

1451182

CC14A
Dual specificity protein phosphatase CDC14A

1

0

High-throughput

0.458

High

245012

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

533783

CLUS
Clusterin

1

0

High-throughput

0.426

High

1406267

KIF2C
Kinesin-like protein KIF2C

1

0

High-throughput

0.426

High

1216335

IFFO2
Intermediate filament family orphan 2

1

1

High-throughput

0.407

High

1451187

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

1

High-throughput

0.407

High

1336691

EHBP1
EH domain-binding protein 1

4

0

High-throughput

0.360

High

1451178

STX18
Syntaxin-18

4

0

High-throughput

0.360

High

270690

ATP9A
Probable phospholipid-transporting ATPase IIA

3

0

High-throughput

0.347

High

284477

HSBP1
Heat shock factor-binding protein 1

3

0

High-throughput

0.347

High

1033436

CDR2
Cerebellar degeneration-related protein 2

3

0

High-throughput

0.347

High

1432861

CENPH
Centromere protein H

3

0

High-throughput

0.347

High

1451184

COG6
Conserved oligomeric Golgi complex subunit 6

3

0

High-throughput

0.347

High

1389697

SGF29
SAGA-associated factor 29

3

0

High-throughput

0.345

High

1248499

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.328

High

1358244

SKA2
Spindle and kinetochore-associated protein 2

2

0

High-throughput

0.316

High

1258696

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

2

0

High-throughput

0.313

High

871184

TFPI2
Tissue factor pathway inhibitor 2

1

0

High-throughput

0.279

Low

1198861

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

0

High-throughput

0.279

Low

1308516

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.279

Low

1331612

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

0

High-throughput

0.279

Low

1397254

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.279

Low

1410535

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1428557

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.279

Low

69411

WASH1
WASH complex subunit 1

1

0

High-throughput

0.251

Low

278982

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.249

Low

316069

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

437368

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.249

Low

475706

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.249

Low

1153933

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.249

Low

1194086

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

Small-scale

0.249

Low

1392352

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

1451179

ZO2
Tight junction protein 2

1

0

High-throughput

0.249

Low

1232792

Q6FII1
Glutathione S-transferase kappa

1

0

High-throughput

0.238

Low

273110

CLU
Clustered mitochondria protein homolog

1

0

High-throughput

0.232

Low

366505

UROK
Urokinase-type plasminogen activator

1

0

High-throughput

0.232

Low

1167122

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1307488

MY18B
Unconventional myosin-XVIIIb

1

0

High-throughput

0.232

Low

1450274

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.232

Low

1451176

SELN
Selenoprotein N

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025