Protein: MAOM
NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2)

Gene: MAOM, ME2
Organism: Homo sapiens
Interactions: 83
UniProt ID: P23368

Gene Ontology (top 5):
GO:0004470 - malic enzyme activity
GO:0004471 - malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004473 - malate dehydrogenase (decarboxylating) (NADP+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

657382

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

0

High-throughput

0.585

High

279651

CISY
Citrate synthase, mitochondrial

2

2

High-throughput

0.584

High

532363

CH60
60 kDa heat shock protein, mitochondrial

2

1

High-throughput

0.571

High

657371

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

657373

MYLK
Myosin light chain kinase, smooth muscle

1

0

High-throughput

0.513

High

657411

IFT25
Intraflagellar transport protein 25 homolog

1

0

High-throughput

0.513

High

657395

KDM4C
Lysine-specific demethylase 4C

1

1

High-throughput

0.489

High

240770

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

281883

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287238

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.479

High

348366

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

411363

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

470854

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

657351

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

657353

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

657354

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

657366

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

657367

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

657370

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

657375

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

657384

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

657385

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

657387

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

657392

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

657394

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

657397

MTG2
Mitochondrial ribosome-associated GTPase 2

1

3

High-throughput

0.479

High

657400

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

657404

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

1

High-throughput

0.479

High

657406

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

657410

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.479

High

350789

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

519048

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

559868

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

657355

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

657356

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.458

High

657357

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

657359

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

657364

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

657365

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

657372

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

657374

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

657378

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

657386

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

657388

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

657390

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

657391

TR61B
tRNA

1

0

High-throughput

0.458

High

657393

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

657398

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

657399

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

657402

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

657403

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

657409

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

185432

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.457

High

529091

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

657360

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

657362

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

2

High-throughput

0.445

High

657401

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

657412

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

2

High-throughput

0.445

High

105350

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

587930

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

657349

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

657352

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

657376

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.437

High

657380

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

657383

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.437

High

657389

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.437

High

657407

XPO7
Exportin-7

1

1

High-throughput

0.437

High

653131

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

657368

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.426

High

657377

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

657379

T184A
Transmembrane protein 184A

2

0

High-throughput

0.328

High

657358

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

156005

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.269

Low

345379

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

536514

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

657350

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

High-throughput

0.249

Low

657361

KLF3
Krueppel-like factor 3

1

0

High-throughput

0.249

Low

657363

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

657369

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

657381

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

657396

WNK1
Serine/threonine-protein kinase WNK1

1

0

High-throughput

0.249

Low

657405

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

657408

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025