Protein: LCA5
Lebercilin (Leber congenital amaurosis 5 protein)

Gene: LCA5
Organism: Homo sapiens
Interactions: 124
UniProt ID: Q86VQ0

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0005813 - centrosome
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1291372

RCOR3
REST corepressor 3

3

4

High-throughput

0.675

High

1143389

PCM1
Pericentriolar material 1 protein

3

2

High-throughput

0.657

High

1291343

DYL2
Dynein light chain 2, cytoplasmic

3

4

High-throughput

0.656

High

1291374

TFP11
Tuftelin-interacting protein 11

3

3

High-throughput

0.653

High

991605

DYL1
Dynein light chain 1, cytoplasmic

3

4

High-throughput

0.650

High

1291355

IFT27
Intraflagellar transport protein 27 homolog

3

9

High-throughput

0.650

High

1291324

ARMC8
Armadillo repeat-containing protein 8

2

3

High-throughput

0.628

High

1291359

TSYL1
Testis-specific Y-encoded-like protein 1

2

5

High-throughput

0.628

High

966558

1433G
14-3-3 protein gamma

4

20

High-throughput

0.619

High

228034

SSNA1
Microtubule nucleation factor SSNA1

2

0

High-throughput

0.602

High

334825

IPO7
Importin-7

2

8

High-throughput

0.588

High

1049507

1433F
14-3-3 protein eta

2

20

High-throughput

0.588

High

1291357

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

4

High-throughput

0.588

High

1291378

SUFU
Suppressor of fused homolog

2

0

High-throughput

0.580

High

61543

VWA8
von Willebrand factor A domain-containing protein 8

2

7

High-throughput

0.571

High

130527

SPT5H
Transcription elongation factor SPT5

2

5

High-throughput

0.571

High

134079

IPO5
Importin-5

2

4

High-throughput

0.571

High

572048

TRI27
Zinc finger protein RFP

2

10

High-throughput

0.571

High

730016

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.571

High

733957

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

2

2

High-throughput

0.571

High

960475

PSME3
Proteasome activator complex subunit 3

2

4

High-throughput

0.571

High

990441

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.571

High

1038656

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

2

5

High-throughput

0.571

High

1048584

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

3

High-throughput

0.571

High

1066142

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

2

2

High-throughput

0.571

High

1094460

IFT88
Intraflagellar transport protein 88 homolog

2

4

High-throughput

0.571

High

1134265

IMB1
Importin subunit beta-1

2

7

High-throughput

0.571

High

1152135

MARE1
Microtubule-associated protein RP/EB family member 1

2

1

High-throughput

0.571

High

1291330

MIPT3
TRAF3-interacting protein 1

2

4

High-throughput

0.571

High

1291334

IFT81
Intraflagellar transport protein 81 homolog

2

19

High-throughput

0.571

High

1291344

IFT74
Intraflagellar transport protein 74 homolog

2

20

High-throughput

0.571

High

1291354

NOC4L
Nucleolar complex protein 4 homolog

2

3

High-throughput

0.571

High

1291361

IFT22
Intraflagellar transport protein 22 homolog

2

4

High-throughput

0.571

High

1291362

XPO5
Exportin-5

2

6

High-throughput

0.571

High

1291371

IFT80
Intraflagellar transport protein 80 homolog

2

14

High-throughput

0.571

High

1291375

SAE2
SUMO-activating enzyme subunit 2

2

1

High-throughput

0.571

High

1291376

IF172
Intraflagellar transport protein 172 homolog

2

12

High-throughput

0.571

High

290064

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.554

High

1210896

CE170
Centrosomal protein of 170 kDa

1

14

High-throughput

0.554

High

1291339

GCC1
GRIP and coiled-coil domain-containing protein 1

2

19

High-throughput

0.553

High

1006517

SRPK2
SRSF protein kinase 2

1

17

High-throughput

0.550

High

48153

IFT56
Intraflagellar transport protein 56

2

0

High-throughput

0.547

High

211652

ZNHI1
Zinc finger HIT domain-containing protein 1

2

0

High-throughput

0.547

High

1168528

KNOP1
Lysine-rich nucleolar protein 1

2

0

High-throughput

0.547

High

1291323

IT70A
Intraflagellar transport protein 70A

2

0

High-throughput

0.547

High

1291326

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.547

High

1291333

BRI3B
BRI3-binding protein

2

0

High-throughput

0.547

High

1291337

CLUA1
Clusterin-associated protein 1

2

0

High-throughput

0.547

High

1291342

PTCD3
Small ribosomal subunit protein mS39

2

0

High-throughput

0.547

High

1291366

IFT46
Intraflagellar transport protein 46 homolog

2

0

High-throughput

0.547

High

1291367

IFT57
Intraflagellar transport protein 57 homolog

2

0

High-throughput

0.547

High

1291379

CSN3
COP9 signalosome complex subunit 3

2

0

High-throughput

0.547

High

1291385

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

2

0

High-throughput

0.547

High

1291348

NP1L4
Nucleosome assembly protein 1-like 4

2

6

High-throughput

0.537

High

1272697

MAEA
E3 ubiquitin-protein transferase MAEA

1

1

High-throughput

0.536

High

1177958

MOONR
Protein moonraker

1

0

High-throughput

0.530

High

1291381

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.530

High

821139

TXLNA
Alpha-taxilin

1

19

High-throughput

0.523

High

291416

NU155
Nuclear pore complex protein Nup155

2

3

High-throughput

0.521

High

608154

PYRG1
CTP synthase 1

2

1

High-throughput

0.521

High

691196

1433T
14-3-3 protein theta

2

20

High-throughput

0.521

High

971729

1433E
14-3-3 protein epsilon

2

4

High-throughput

0.521

High

1143958

IPYR
Inorganic pyrophosphatase

2

1

High-throughput

0.521

High

1145611

RCN1
Reticulocalbin-1

2

5

High-throughput

0.521

High

1246130

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

14

High-throughput

0.521

High

1291340

KCD12
BTB/POZ domain-containing protein KCTD12

2

16

High-throughput

0.521

High

1291363

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

2

2

High-throughput

0.521

High

1291384

IFT25
Intraflagellar transport protein 25 homolog

1

0

High-throughput

0.513

High

159730

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

10

High-throughput

0.479

High

177251

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

7

High-throughput

0.479

High

189208

IPO8
Importin-8

1

6

High-throughput

0.479

High

214594

WDR62
WD repeat-containing protein 62

1

15

High-throughput

0.479

High

766673

PHB1
Prohibitin 1

1

8

High-throughput

0.479

High

920084

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

967483

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

1169009

CSPP1
Centrosome and spindle pole-associated protein 1

1

1

High-throughput

0.479

High

1186273

MA7D1
MAP7 domain-containing protein 1

1

18

High-throughput

0.479

High

1215467

CE162
Centrosomal protein of 162 kDa

1

19

High-throughput

0.479

High

1228429

FTM
Protein fantom

1

20

High-throughput

0.479

High

1278401

HAUS6
HAUS augmin-like complex subunit 6

1

1

High-throughput

0.479

High

1289937

LUZP1
Leucine zipper protein 1

1

19

High-throughput

0.479

High

1291327

NIN
Ninein

1

18

High-throughput

0.479

High

1291328

CE120
Centrosomal protein of 120 kDa

1

18

High-throughput

0.479

High

1291329

NEDD1
Protein NEDD1

1

11

High-throughput

0.479

High

1291332

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.479

High

1291336

MRTFA
Myocardin-related transcription factor A

1

12

High-throughput

0.479

High

1291341

TBC31
TBC1 domain family member 31

1

16

High-throughput

0.479

High

1291347

MA7D2
MAP7 domain-containing protein 2

1

20

High-throughput

0.479

High

1291350

GPTC1
G patch domain-containing protein 1

1

4

High-throughput

0.479

High

1291353

TCHP
Trichoplein keratin filament-binding protein

1

19

High-throughput

0.479

High

1291364

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.479

High

1291368

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.479

High

1291369

CEP72
Centrosomal protein of 72 kDa

1

7

High-throughput

0.479

High

1291373

WRP73
WD repeat-containing protein WRAP73

1

13

High-throughput

0.479

High

1291377

MTUS1
Microtubule-associated tumor suppressor 1

1

18

High-throughput

0.479

High

1291380

CP131
Centrosomal protein of 131 kDa

1

19

High-throughput

0.479

High

1291382

NINL
Ninein-like protein

1

19

High-throughput

0.479

High

60794

CCD66
Coiled-coil domain-containing protein 66

1

0

High-throughput

0.458

High

1185266

F161A
Protein FAM161A

1

0

Small-scale

0.458

High

1228542

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1291322

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.458

High

1291331

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.458

High

1291335

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

0

High-throughput

0.458

High

1291338

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.458

High

1291349

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

1291352

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

1291358

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1291360

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

176847

DCLK1
Serine/threonine-protein kinase DCLK1

1

4

High-throughput

0.437

High

936797

NP1L1
Nucleosome assembly protein 1-like 1

1

6

High-throughput

0.437

High

1089228

TRI26
Tripartite motif-containing protein 26

1

11

High-throughput

0.437

High

1124483

MAP7
Ensconsin

1

20

High-throughput

0.437

High

1140502

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.437

High

1291325

MA7D3
MAP7 domain-containing protein 3

1

10

High-throughput

0.437

High

1291351

WDR83
WD repeat domain-containing protein 83

1

17

High-throughput

0.437

High

1291356

TRIM2
Tripartite motif-containing protein 2

1

14

High-throughput

0.437

High

1291365

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.437

High

1291383

C170B
Centrosomal protein of 170 kDa protein B

1

11

High-throughput

0.437

High

365417

PGK1
Phosphoglycerate kinase 1

2

0

High-throughput

0.298

High

1291346

VPS35
Vacuolar protein sorting-associated protein 35

2

0

High-throughput

0.298

High

1193648

MAP9
Microtubule-associated protein 9

1

0

High-throughput

0.249

Low

1213175

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

0

High-throughput

0.249

Low

1291345

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1291370

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025