Protein: DHC24
Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol Delta-24-reductase) (Diminuto/dwarf1 homolog) (Seladin-1)

Gene: DHC24, DHCR24
Organism: Homo sapiens
Interactions: 222
UniProt ID: Q15392

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000246 - delta24(24-1) sterol reductase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

915389

ACTA
Actin, aortic smooth muscle

3

1

High-throughput

0.667

High

1072912

LUZP1
Leucine zipper protein 1

3

2

High-throughput

0.667

High

1072975

ERAP1
Endoplasmic reticulum aminopeptidase 1

3

0

High-throughput

0.638

High

123607

PGRC1
Membrane-associated progesterone receptor component 1

3

0

High-throughput

0.634

High

848548

CAV2
Caveolin-2

3

0

High-throughput

0.622

High

961667

REEP5
Receptor expression-enhancing protein 5

3

0

High-throughput

0.622

High

1072949

FUND2
FUN14 domain-containing protein 2

2

1

High-throughput

0.611

High

871908

AT12A
Potassium-transporting ATPase alpha chain 2

3

3

High-throughput

0.609

High

307043

RTN3
Reticulon-3

2

3

High-throughput

0.601

High

1072967

RTN4
Reticulon-4

2

3

High-throughput

0.601

High

349335

RASH
GTPase HRas

2

0

High-throughput

0.585

High

899962

VA0D1
V-type proton ATPase subunit d 1

2

0

High-throughput

0.585

High

48364

ESYT2
Extended synaptotagmin-2

2

1

High-throughput

0.571

High

369660

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1072921

DHB11
Estradiol 17-beta-dehydrogenase 11

2

3

High-throughput

0.571

High

386783

P53
Cellular tumor antigen p53

2

0

Small-scale

0.559

High

158477

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

High-throughput

0.536

High

172004

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.536

High

326071

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

530892

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

3

High-throughput

0.536

High

626518

FPR2
N-formyl peptide receptor 2

1

3

High-throughput

0.536

High

654357

CALX
Calnexin

1

1

High-throughput

0.536

High

714662

CNR2
Cannabinoid receptor 2

1

2

Small-scale

0.536

High

725453

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.536

High

863444

COPA
Coatomer subunit alpha

1

2

High-throughput

0.536

High

1047735

CKAP5
Cytoskeleton-associated protein 5

1

1

High-throughput

0.536

High

1072899

RTN1
Reticulon-1

1

3

High-throughput

0.536

High

1072930

SPP2B
Signal peptide peptidase-like 2B

1

1

High-throughput

0.536

High

1072935

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.536

High

1072936

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.536

High

1072963

AT133
Polyamine-transporting ATPase 13A3

1

4

High-throughput

0.536

High

1072965

LPAR2
Lysophosphatidic acid receptor 2

1

2

High-throughput

0.536

High

394750

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.530

High

834288

PSN1
Presenilin-1

1

0

High-throughput

0.530

High

118959

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.513

High

149643

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

213122

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

281634

WFS1
Wolframin

1

0

High-throughput

0.513

High

300575

ENDD1
Endonuclease domain-containing 1 protein

1

0

High-throughput

0.513

High

375747

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.513

High

376465

APOB
Apolipoprotein B-100

1

0

High-throughput

0.513

High

392681

B3A2
Anion exchange protein 2

1

0

High-throughput

0.513

High

412204

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.513

High

505400

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.513

High

586767

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

735953

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.513

High

742310

SYUA
Alpha-synuclein

1

0

High-throughput

0.513

High

786355

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

High-throughput

0.513

High

792779

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

873923

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.513

High

1053754

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1072918

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1072924

ZNT7
Zinc transporter 7

1

0

High-throughput

0.513

High

1072943

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

1072954

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1072958

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1072961

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

536626

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.493

High

1068243

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.493

High

156831

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.489

High

686293

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

1

High-throughput

0.489

High

782424

P2RY2
P2Y purinoceptor 2

1

2

High-throughput

0.489

High

783641

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

1

High-throughput

0.489

High

814575

P2RY1
P2Y purinoceptor 1

1

2

High-throughput

0.489

High

1072904

RABL3
Rab-like protein 3

1

3

High-throughput

0.489

High

1072914

FUND1
FUN14 domain-containing protein 1

1

1

High-throughput

0.489

High

1072917

FCSK
L-fucose kinase

1

1

High-throughput

0.489

High

130901

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

3

High-throughput

0.479

High

163815

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

227525

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

273811

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

338464

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

509667

UBL4A
Ubiquitin-like protein 4A

1

4

High-throughput

0.479

High

552795

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

651278

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

718880

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

900498

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

940936

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1035771

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1041633

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1066151

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1072908

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1072931

RBCC1
RB1-inducible coiled-coil protein 1

1

2

High-throughput

0.479

High

1072955

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.479

High

1072960

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1072982

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1072983

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

125476

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

167924

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

262823

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

322668

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

359968

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

573706

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

590944

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

779464

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

785931

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

873127

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

0

High-throughput

0.458

High

890167

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

903244

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

917313

H4
Histone H4

1

0

High-throughput

0.458

High

967879

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1040111

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1064325

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1072903

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.458

High

1072907

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1072910

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1072913

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.458

High

1072937

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1072941

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1072948

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1072962

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1072964

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1072969

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.458

High

1072976

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1072981

DHCR7
7-dehydrocholesterol reductase

1

0

Small-scale

0.458

High

1072984

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

1072985

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

High-throughput

0.458

High

1072989

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

50150

HACL2
2-hydroxyacyl-CoA lyase 2

1

2

High-throughput

0.445

High

99793

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.445

High

199337

ZW10
Centromere/kinetochore protein zw10 homolog

1

1

High-throughput

0.445

High

258930

RTN2
Reticulon-2

1

3

High-throughput

0.445

High

310648

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

335428

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.445

High

397982

ISG15
Ubiquitin-like protein ISG15

1

3

Small-scale

0.445

High

414506

PRGR
Progesterone receptor

1

1

Small-scale

0.445

High

502131

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.445

High

653601

CALR
Calreticulin

1

1

High-throughput

0.445

High

833224

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

887858

CD81
CD81 antigen

1

1

High-throughput

0.445

High

924006

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

3

High-throughput

0.445

High

1032418

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

1062521

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.445

High

1071766

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

1072898

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

1

High-throughput

0.445

High

1072901

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

4

High-throughput

0.445

High

1072905

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

1072916

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

3

High-throughput

0.445

High

1072926

ATLA2
Atlastin-2

1

2

High-throughput

0.445

High

1072932

SCFD1
Sec1 family domain-containing protein 1

1

1

High-throughput

0.445

High

1072933

ATLA1
Atlastin-1

1

2

High-throughput

0.445

High

1072940

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

1072946

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.445

High

1072951

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.445

High

1072953

RGAP1
Rac GTPase-activating protein 1

1

1

High-throughput

0.445

High

1072959

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.445

High

1072979

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

1072980

COPG2
Coatomer subunit gamma-2

1

2

High-throughput

0.445

High

1072987

DHRS7
Dehydrogenase/reductase SDR family member 7

1

3

High-throughput

0.445

High

1072988

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.445

High

1072992

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

434203

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

2

High-throughput

0.437

High

720533

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1072915

S15A3
Solute carrier family 15 member 3

1

2

High-throughput

0.437

High

58090

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

202894

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

266163

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

277068

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.426

High

297753

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.426

High

432729

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

532127

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.426

High

818945

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

822030

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

827797

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

847277

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.426

High

847483

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

863236

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

902314

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

945845

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

1026689

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

1058428

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

1065249

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

1065362

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1070820

RCN1
Reticulocalbin-1

1

0

High-throughput

0.426

High

1072906

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

1072919

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

1072920

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.426

High

1072922

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

1072923

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

1072927

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.426

High

1072938

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.426

High

1072939

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

1072944

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.426

High

1072945

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.426

High

1072947

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

1072952

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

1072956

S38A1
Sodium-coupled neutral amino acid symporter 1

1

0

High-throughput

0.426

High

1072957

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1072966

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.426

High

1072970

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

1072971

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.426

High

1072972

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.426

High

1072974

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

1072991

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

99605

F5H1C8
Solute carrier family 15 member 3

1

2

High-throughput

0.407

High

201020

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

1

High-throughput

0.407

High

950621

ARF5
ADP-ribosylation factor 5

1

1

High-throughput

0.407

High

1072909

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.407

High

1072973

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.407

High

849626

CCR4
C-C chemokine receptor type 4

1

0

High-throughput

0.282

High

299161

CSCL1
CSC1-like protein 1

1

0

High-throughput

0.279

Low

439122

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

579540

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.279

Low

770220

GPV
Platelet glycoprotein V

1

0

High-throughput

0.279

Low

965683

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.279

Low

1072928

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

0

High-throughput

0.279

Low

1072934

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1072950

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

1072978

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.279

Low

1072990

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

130505

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.249

Low

258450

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

473393

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.249

Low

1072900

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1072902

AGK
Acylglycerol kinase, mitochondrial

1

0

Small-scale

0.249

Low

1072911

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

1072929

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1072977

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.249

Low

1072986

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1072968

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

1072925

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.232

Low

1072942

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024