Protein: IFRD2
Interferon-related developmental regulator 2 (Protein SKMC15)

Gene: IFRD2
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q12894

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0016055 - Wnt signaling pathway
GO:0017148 - negative regulation of translation
GO:0030371 - translation repressor activity
GO:0043022 - ribosome binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1089183

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

3

0

Small-scale

0.652

High

1089181

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

396003

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1089187

HDAC6
Protein deacetylase HDAC6

1

4

High-throughput

0.536

High

446956

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

1089174

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1089186

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.513

High

286802

JERKY
Jerky protein homolog

1

0

High-throughput

0.493

High

185646

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

286963

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

2

High-throughput

0.479

High

695322

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

1008704

RED1
Double-stranded RNA-specific editase 1

1

1

High-throughput

0.479

High

1089173

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

1089188

XPO7
Exportin-7

1

1

High-throughput

0.479

High

241530

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

1045228

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1089182

AASD1
Alanyl-tRNA editing protein Aarsd1

1

0

High-throughput

0.458

High

1089179

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.457

High

1089175

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

295323

EIF3J
Eukaryotic translation initiation factor 3 subunit J

2

0

High-throughput

0.328

High

1089189

OAS3
2'-5'-oligoadenylate synthase 3

1

0

High-throughput

0.306

High

1089184

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.288

High

1089180

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1089185

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.279

Low

48289

E2F8
Transcription factor E2F8

1

0

High-throughput

0.269

Low

422014

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

879023

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1089176

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.249

Low

1089178

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

262222

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.232

Low

437669

HEPS
Serine protease hepsin

1

0

High-throughput

0.232

Low

640156

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.232

Low

683231

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.232

Low

1089177

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025