Protein: APC5
Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)

Gene: APC5, ANAPC5
Organism: Homo sapiens
Interactions: 124
UniProt ID: Q9UJX4

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005819 - spindle
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1356142

APC4
Anaphase-promoting complex subunit 4

9

1

Small-scale

0.967

High

1356110

CDC23
Cell division cycle protein 23 homolog

4

12

High-throughput

0.900

High

1328553

APC1
Anaphase-promoting complex subunit 1

4

1

Small-scale

0.875

High

887628

APC15
Anaphase-promoting complex subunit 15

3

0

Small-scale

0.816

High

672918

CDC27
Cell division cycle protein 27 homolog

19

9

Small-scale

0.763

High

1356143

ANC2
Anaphase-promoting complex subunit 2

6

4

Small-scale

0.729

High

1017460

CDC20
Cell division cycle protein 20 homolog

6

5

Small-scale

0.724

High

1023017

CDC16
Cell division cycle protein 16 homolog

5

12

High-throughput

0.720

High

1356146

FZR1
Fizzy-related protein homolog

5

5

Small-scale

0.713

High

851367

NEK2
Serine/threonine-protein kinase Nek2

3

1

Small-scale

0.656

High

1356151

LMBL1
Lethal(3)malignant brain tumor-like protein 1

3

0

High-throughput

0.646

High

1288137

APC16
Anaphase-promoting complex subunit 16

3

0

High-throughput

0.638

High

1246279

CDC26
Anaphase-promoting complex subunit CDC26

3

0

High-throughput

0.634

High

1310885

APC13
Anaphase-promoting complex subunit 13

3

0

High-throughput

0.634

High

1344965

LATS2
Serine/threonine-protein kinase LATS2

3

0

Small-scale

0.634

High

1356133

APC7
Anaphase-promoting complex subunit 7

3

12

Small-scale

0.633

High

1356145

FBX5
F-box only protein 5

2

0

Small-scale

0.612

High

275237

GRAP2
GRB2-related adapter protein 2

2

2

High-throughput

0.611

High

1117510

ANO6
Anoctamin-6

2

0

High-throughput

0.602

High

1327432

IQCN
IQ domain-containing protein N

2

0

High-throughput

0.602

High

1356150

CRYL1
Lambda-crystallin homolog

2

0

High-throughput

0.602

High

236989

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

2

1

High-throughput

0.601

High

391960

H2A1B
Histone H2A type 1-B/E

2

0

High-throughput

0.585

High

1057018

MDC1
Mediator of DNA damage checkpoint protein 1

2

2

Small-scale

0.584

High

370668

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1269883

ESR2
Estrogen receptor beta

2

1

High-throughput

0.571

High

1270828

CBP
CREB-binding protein

1

3

Small-scale

0.561

High

963698

E2F1
Transcription factor E2F1

2

0

Small-scale

0.559

High

1198287

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

2

0

Small-scale

0.559

High

516732

PABP1
Polyadenylate-binding protein 1

1

0

Small-scale

0.549

High

1044248

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

0

High-throughput

0.547

High

1043288

CUL4A
Cullin-4A

1

1

High-throughput

0.536

High

1356147

APC10
Anaphase-promoting complex subunit 10

1

3

High-throughput

0.536

High

890885

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.530

High

157255

BACH1
Transcription regulator protein BACH1

1

0

High-throughput

0.518

High

984040

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.518

High

175510

RA51B
DNA repair protein RAD51 homolog 2

1

0

High-throughput

0.513

High

230532

TRAK2
Trafficking kinesin-binding protein 2

1

0

High-throughput

0.513

High

277373

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

324105

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

504924

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

804366

NOTC1
Neurogenic locus notch homolog protein 1

1

0

High-throughput

0.513

High

818583

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

828934

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

846543

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.513

High

929101

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.513

High

1029347

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1073181

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.513

High

1087468

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1152406

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1159708

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

1295204

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

1306175

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1311637

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

1316228

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1318421

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1332130

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

1356144

HSPB8
Heat shock protein beta-8

1

0

High-throughput

0.513

High

1347047

RBM28
RNA-binding protein 28

1

1

High-throughput

0.489

High

1085539

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.486

High

970611

ID2
DNA-binding protein inhibitor ID-2

1

0

Small-scale

0.480

High

1086940

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

0

Small-scale

0.480

High

163438

XPO1
Exportin-1

1

1

High-throughput

0.479

High

643619

PTBP1
Polypyrimidine tract-binding protein 1

1

1

High-throughput

0.479

High

851389

NEK3
Serine/threonine-protein kinase Nek3

1

1

High-throughput

0.479

High

999189

EP300
Histone acetyltransferase p300

1

4

Small-scale

0.479

High

1019166

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1042801

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1067184

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

1173269

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.479

High

1242687

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

2

Small-scale

0.479

High

1285218

SH3K1
SH3 domain-containing kinase-binding protein 1

1

1

High-throughput

0.479

High

1334853

PKHA5
Pleckstrin homology domain-containing family A member 5

1

1

Small-scale

0.479

High

1356148

TRI33
E3 ubiquitin-protein ligase TRIM33

1

1

Small-scale

0.479

High

208308

DCX
Neuronal migration protein doublecortin

1

0

Small-scale

0.458

High

272755

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

295373

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

299486

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

319371

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

554013

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652557

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

656332

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.458

High

721734

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

780292

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

910611

RS14
Small ribosomal subunit protein uS11

1

0

Small-scale

0.458

High

918109

H4
Histone H4

1

0

High-throughput

0.458

High

935354

H31
Histone H3.1

1

0

High-throughput

0.458

High

1035040

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1050549

TFDP1
Transcription factor Dp-1

1

0

Small-scale

0.458

High

1189009

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1219390

CUL9
Cullin-9

1

0

Small-scale

0.458

High

1236561

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1253582

CMAP3
Ciliary microtubule-associated protein 3

1

0

High-throughput

0.458

High

1314419

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1328974

CDT1
DNA replication factor Cdt1

1

0

Small-scale

0.458

High

1330546

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1331256

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

0

High-throughput

0.458

High

1332745

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1348898

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1356149

PHF8
Histone lysine demethylase PHF8

1

0

Small-scale

0.458

High

1117529

Q4KMX6
ANAPC7 protein

1

12

High-throughput

0.445

High

1331582

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

48745

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

211274

BUB3
Mitotic checkpoint protein BUB3

1

0

High-throughput

0.426

High

1123558

HS904
Putative heat shock protein HSP 90-alpha A4

1

0

High-throughput

0.426

High

345204

KNG1
Kininogen-1

3

0

High-throughput

0.347

High

351628

PENK
Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin

3

0

High-throughput

0.347

High

1332588

MAGIX
PDZ domain-containing protein MAGIX

3

0

High-throughput

0.347

High

1161483

CP087
UPF0547 protein C16orf87

2

0

High-throughput

0.328

High

1244900

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

327755

TTLL1
Polyglutamylase complex subunit TTLL1

2

0

High-throughput

0.318

High

276286

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.279

Low

1100172

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1132271

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

1150186

ATLA3
Atlastin-3

1

0

High-throughput

0.279

Low

1282313

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

1296573

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

1302187

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

1336463

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1350225

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.279

Low

1166054

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1172192

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1350498

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

1349909

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024