Protein: PAXB1
PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1)

Gene: PAXB1, PAXBP1
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q9Y5B6

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006366 - transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1288410

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

4

1

High-throughput

0.694

High

1313234

DDX23
Probable ATP-dependent RNA helicase DDX23

4

1

High-throughput

0.694

High

912009

RUXF
Small nuclear ribonucleoprotein F

3

1

High-throughput

0.675

High

1288062

HDA11
Histone deacetylase 11

3

1

High-throughput

0.675

High

1294820

RSRC1
Serine/Arginine-related protein 53

3

0

High-throughput

0.638

High

539205

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

2

High-throughput

0.628

High

911780

RUXE
Small nuclear ribonucleoprotein E

2

1

High-throughput

0.628

High

928050

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

2

High-throughput

0.628

High

943049

SRPK2
SRSF protein kinase 2

2

1

High-throughput

0.628

High

912135

RUXG
Small nuclear ribonucleoprotein G

2

5

High-throughput

0.611

High

1064901

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

1

High-throughput

0.611

High

1157409

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

0

High-throughput

0.602

High

1377957

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

2

0

High-throughput

0.585

High

370814

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

313380

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

1

High-throughput

0.536

High

446857

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.536

High

453943

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.536

High

912212

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

3

High-throughput

0.536

High

912766

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

High-throughput

0.536

High

993880

SRSF4
Serine/arginine-rich splicing factor 4

1

1

High-throughput

0.536

High

1029177

SRSF6
Serine/arginine-rich splicing factor 6

1

1

High-throughput

0.536

High

1357648

SRPK3
SRSF protein kinase 3

1

1

High-throughput

0.536

High

241920

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.513

High

268915

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

448870

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

498383

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

0

High-throughput

0.513

High

801482

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

824686

MAPK2
MAP kinase-activated protein kinase 2

1

0

High-throughput

0.513

High

1074281

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1294413

GPTC3
G patch domain-containing protein 3

1

0

High-throughput

0.513

High

1357083

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

1054712

RBM39
RNA-binding protein 39

1

1

High-throughput

0.489

High

298927

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

309190

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.479

High

348355

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

375156

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

380072

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

442634

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

487874

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

554161

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

652721

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

980921

TLE3
Transducin-like enhancer protein 3

1

2

High-throughput

0.479

High

1018775

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

1055526

DHX8
ATP-dependent RNA helicase DHX8

1

3

High-throughput

0.479

High

1059968

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

1159360

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

1244600

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1270031

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1355005

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1357568

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.479

High

1346745

DJC17
DnaJ homolog subfamily C member 17

1

1

High-throughput

0.470

High

123128

MEN1
Menin

1

0

High-throughput

0.458

High

149470

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

304413

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.458

High

320072

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

718368

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.458

High

824586

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

909400

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

918209

H4
Histone H4

1

0

High-throughput

0.458

High

932476

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

959797

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1036247

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1063711

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1066948

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1075040

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.458

High

1080525

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1198296

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

1221878

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1256515

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1271220

RBP56
TATA-binding protein-associated factor 2N

1

0

High-throughput

0.458

High

1294184

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1307082

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1310573

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1335264

RC3H2
Roquin-2

1

0

High-throughput

0.458

High

1345473

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1348405

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

68471

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

5

High-throughput

0.445

High

195584

DHX15
ATP-dependent RNA helicase DHX15

1

2

Small-scale

0.445

High

1353907

TFP11
Tuftelin-interacting protein 11

1

2

Small-scale

0.445

High

1344870

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

721887

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1172438

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1220326

DHX40
Probable ATP-dependent RNA helicase DHX40

1

3

High-throughput

0.437

High

1357034

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

402676

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

968675

TAGL
Transgelin

1

0

High-throughput

0.426

High

49753

S22AN
Solute carrier family 22 member 23

2

0

High-throughput

0.328

High

1284580

K1143
Uncharacterized protein KIAA1143

2

0

High-throughput

0.328

High

1295300

JPH4
Junctophilin-4

2

0

High-throughput

0.328

High

1022791

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1285106

ARRD3
Arrestin domain-containing protein 3

1

0

High-throughput

0.279

Low

1285626

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1290861

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.279

Low

1201809

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024