Protein: TPRA1
Transmembrane protein adipocyte-associated 1 (Integral membrane protein GPR175) (Transmembrane protein 227)

Gene: TPRA1
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q86W33

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0006629 - lipid metabolic process
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

320466

TM63A
Mechanosensitive cation channel TMEM63A

2

1

High-throughput

0.628

High

1212263

TM63B
Mechanosensitive cation channel TMEM63B

2

1

High-throughput

0.628

High

1292013

ZNT5
Proton-coupled zinc antiporter SLC30A5

2

1

High-throughput

0.628

High

1292024

AT133
Polyamine-transporting ATPase 13A3

2

2

High-throughput

0.628

High

128540

BMR1B
Bone morphogenetic protein receptor type-1B

2

0

High-throughput

0.602

High

295920

SC5D
Lathosterol oxidase

2

0

High-throughput

0.602

High

869615

SC6A8
Sodium- and chloride-dependent creatine transporter 1

2

0

High-throughput

0.602

High

1238343

RETST
All-trans-retinol 13,14-reductase

2

0

High-throughput

0.602

High

1276190

ATG9A
Autophagy-related protein 9A

2

0

High-throughput

0.602

High

1292014

SPPL3
Signal peptide peptidase-like 3

2

0

High-throughput

0.602

High

1292016

TM143
Transmembrane protein 143

2

0

High-throughput

0.602

High

1292020

S12A9
Solute carrier family 12 member 9

2

0

High-throughput

0.602

High

1292021

OSBL8
Oxysterol-binding protein-related protein 8

2

0

High-throughput

0.602

High

123480

GPR25
Probable G-protein coupled receptor 25

2

0

High-throughput

0.580

High

1239509

ZNT6
Zinc transporter 6

2

1

High-throughput

0.574

High

1292019

CP2S1
Cytochrome P450 2S1

2

1

High-throughput

0.574

High

1292025

AT131
Endoplasmic reticulum transmembrane helix translocase

1

2

High-throughput

0.536

High

178315

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.513

High

1101171

CLN3
Battenin

1

0

High-throughput

0.513

High

1128341

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

1

0

High-throughput

0.513

High

1292017

F241B
Protein FAM241B

1

0

High-throughput

0.513

High

1292018

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

0

High-throughput

0.513

High

1292022

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.513

High

1292026

NLGN3
Neuroligin-3

1

0

Small-scale

0.493

High

422477

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

633929

ATP4A
Potassium-transporting ATPase alpha chain 1

1

0

Small-scale

0.458

High

914207

EFNA3
Ephrin-A3

1

0

High-throughput

0.458

High

630864

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.437

High

1292015

SL9A6
Sodium/hydrogen exchanger 6

1

0

High-throughput

0.426

High

1292012

MFSD8
Major facilitator superfamily domain-containing protein 8

2

0

High-throughput

0.328

High

1292023

GHITM
Growth hormone-inducible transmembrane protein

2

0

High-throughput

0.328

High

1292027

DOLK
Dolichol kinase

2

0

High-throughput

0.328

High

1292028

SNX13
Sorting nexin-13

2

0

High-throughput

0.328

High

976379

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025