Protein: DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6 (EC 2.3.1.-) (Diacylglycerol O-acyltransferase candidate 3) (hDC3)

Gene: DG2L6, DGAT2L6
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q6ZPD8

Gene Ontology (top 5):
GO:0004144 - diacylglycerol O-acyltransferase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006629 - lipid metabolic process
GO:0006640 - monoacylglycerol biosynthetic process
GO:0008374 - O-acyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1253297

ABHD4
(Lyso)-N-acylphosphatidylethanolamine lipase

2

1

High-throughput

0.606

High

1253306

RNF5
E3 ubiquitin-protein ligase RNF5

2

1

High-throughput

0.606

High

885165

TTPA
Alpha-tocopherol transfer protein

2

0

High-throughput

0.580

High

898243

R144A
E3 ubiquitin-protein ligase RNF144A

2

0

High-throughput

0.580

High

1253310

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.580

High

1253316

NDRG4
Protein NDRG4

2

0

High-throughput

0.580

High

1253317

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

1134113

NTCP
Hepatic sodium/bile acid cotransporter

2

1

High-throughput

0.553

High

1185977

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.553

High

1253299

ABHD5
1-acylglycerol-3-phosphate O-acyltransferase ABHD5

2

2

High-throughput

0.553

High

1253304

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

2

1

High-throughput

0.553

High

1253308

SNAB
Beta-soluble NSF attachment protein

2

1

High-throughput

0.553

High

46763

A0A384ME17
Elongation factor Tu

1

1

High-throughput

0.470

High

1253302

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

823953

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

882740

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.439

High

181345

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.316

High

329843

SNX4
Sorting nexin-4

2

0

High-throughput

0.316

High

334429

SYFM
Phenylalanine--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

885941

STAR
Steroidogenic acute regulatory protein, mitochondrial

2

0

High-throughput

0.316

High

920572

ARFP2
Arfaptin-2

2

0

High-throughput

0.316

High

944192

SCND1
SCAN domain-containing protein 1

2

0

High-throughput

0.316

High

1023948

EM55
55 kDa erythrocyte membrane protein

2

0

High-throughput

0.316

High

1050853

DCE2
Glutamate decarboxylase 2

2

0

High-throughput

0.316

High

1092015

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

0

High-throughput

0.316

High

1108937

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1219278

ECM29
Proteasome adapter and scaffold protein ECM29

2

0

High-throughput

0.316

High

1243751

FXL19
F-box/LRR-repeat protein 19

2

0

High-throughput

0.316

High

1245821

TMED8
Protein TMED8

2

0

High-throughput

0.316

High

1253294

MTEF4
Transcription termination factor 4, mitochondrial

2

0

High-throughput

0.316

High

1253295

MCEM1
Mast cell-expressed membrane protein 1

2

0

High-throughput

0.316

High

1253296

DHB11
Estradiol 17-beta-dehydrogenase 11

2

0

High-throughput

0.316

High

1253298

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

1253300

T255B
Transmembrane protein 255B

2

0

High-throughput

0.316

High

1253301

THAP4
Peroxynitrite isomerase THAP4

2

0

High-throughput

0.316

High

1253303

TM143
Transmembrane protein 143

2

0

High-throughput

0.316

High

1253305

RUSF1
RUS family member 1

2

0

High-throughput

0.316

High

1253307

SMG9
Nonsense-mediated mRNA decay factor SMG9

2

0

High-throughput

0.316

High

1253309

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

0

High-throughput

0.316

High

1253312

DBLOH
Diablo IAP-binding mitochondrial protein

2

0

High-throughput

0.316

High

1253313

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1253314

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.316

High

1253315

PITC1
Cytoplasmic phosphatidylinositol transfer protein 1

2

0

High-throughput

0.316

High

1253318

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

2

0

High-throughput

0.316

High

272960

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.269

Low

1253311

MYG1
MYG1 exonuclease

1

0

High-throughput

0.268

Low

718705

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.251

Low

1207702

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025