Protein: LSME2
Leucine-rich single-pass membrane protein 2

Gene: LSME2, LSMEM2
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q8N112

Gene Ontology (top 5):
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1322556

LSME1
Leucine-rich single-pass membrane protein 1

3

0

High-throughput

0.646

High

189697

STX7
Syntaxin-7

4

1

High-throughput

0.629

High

60583

TM218
Transmembrane protein 218

2

0

High-throughput

0.580

High

226825

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

0

High-throughput

0.580

High

688398

PPLA
Phospholamban

2

0

High-throughput

0.580

High

932695

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.580

High

1195534

CTXN3
Cortexin-3

2

0

High-throughput

0.580

High

1322564

TM143
Transmembrane protein 143

2

0

High-throughput

0.580

High

1322568

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.580

High

1110804

PKD2
Polycystin-2

2

0

High-throughput

0.576

High

1322557

RN149
E3 ubiquitin-protein ligase RNF149

2

0

High-throughput

0.576

High

1322558

MSPD2
Motile sperm domain-containing protein 2

2

0

High-throughput

0.576

High

641464

CD72
B-cell differentiation antigen CD72

2

1

High-throughput

0.553

High

688590

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

2

1

High-throughput

0.553

High

1177829

CL12B
C-type lectin domain family 12 member B

2

1

High-throughput

0.553

High

535286

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

1186410

ASTRB
Protein Aster-B

1

1

High-throughput

0.536

High

321772

AGRL1
Adhesion G protein-coupled receptor L1

1

0

High-throughput

0.513

High

930987

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

1322569

LMA2L
VIP36-like protein

1

0

High-throughput

0.513

High

1322574

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

1

0

High-throughput

0.513

High

1322575

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.513

High

1322576

ENPP4
Bis(5'-adenosyl)-triphosphatase ENPP4

1

0

High-throughput

0.513

High

1100687

STX3
Syntaxin-3

1

1

High-throughput

0.489

High

1322565

ASTRA
Protein Aster-A

1

1

High-throughput

0.489

High

422558

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1322566

GIMA5
GTPase IMAP family member 5

3

0

High-throughput

0.352

High

337892

CLD7
Claudin-7

2

0

High-throughput

0.316

High

548057

PSPC
Surfactant protein C

2

0

High-throughput

0.316

High

1059080

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.316

High

1322567

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

1322570

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.316

High

1322573

SPG21
Maspardin

2

0

High-throughput

0.316

High

1293257

LSR
Lipolysis-stimulated lipoprotein receptor

2

0

High-throughput

0.313

High

61121

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.279

Low

167754

PCD17
Protocadherin-17

1

0

High-throughput

0.279

Low

278527

VAMP4
Vesicle-associated membrane protein 4

1

0

High-throughput

0.279

Low

282604

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.279

Low

925660

IST1
IST1 homolog

1

0

High-throughput

0.279

Low

1062995

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

High-throughput

0.279

Low

1307879

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.279

Low

1308153

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.279

Low

1322559

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.279

Low

1322560

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

1322562

LMBR1
Limb region 1 protein homolog

1

0

High-throughput

0.279

Low

1322571

XPP3
Xaa-Pro aminopeptidase 3

1

0

High-throughput

0.279

Low

1279197

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.249

Low

1322561

STAG1
Cohesin subunit SA-1

1

0

High-throughput

0.249

Low

1322572

ANLN
Anillin

1

0

High-throughput

0.249

Low

839587

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.232

Low

1242343

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.232

Low

1322563

POF1B
Protein POF1B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025