Protein: ORML1
ORM1-like protein 1 (Adoplin-1)

Gene: ORML1, ORMDL1
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q9P0S3

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006672 - ceramide metabolic process
GO:0006686 - sphingomyelin biosynthetic process
GO:0017059 - serine palmitoyltransferase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

184932

SPTC1
Serine palmitoyltransferase 1

1

8

High-throughput

0.691

High

926862

VMAT1
Chromaffin granule amine transporter

2

8

High-throughput

0.606

High

1142967

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

2

High-throughput

0.606

High

1334044

DHB11
Estradiol 17-beta-dehydrogenase 11

2

1

High-throughput

0.606

High

1384372

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.606

High

1398521

ZDH15
Palmitoyltransferase ZDHHC15

2

1

High-throughput

0.606

High

1434956

REEP4
Receptor expression-enhancing protein 4

2

1

High-throughput

0.606

High

1447900

SAR1A
Small COPII coat GTPase SAR1A

2

2

High-throughput

0.606

High

1453999

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

3

High-throughput

0.606

High

230452

CREB3
Cyclic AMP-responsive element-binding protein 3

2

2

High-throughput

0.590

High

181453

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.580

High

690411

STOM
Stomatin

2

0

High-throughput

0.580

High

1191807

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

2

0

High-throughput

0.580

High

1198911

NACHO
Novel acetylcholine receptor chaperone

2

0

High-throughput

0.580

High

1212770

ZFY27
Protrudin

2

0

High-throughput

0.580

High

1398488

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

1109082

AQP6
Aquaporin-6

2

5

High-throughput

0.553

High

1134181

NTCP
Hepatic sodium/bile acid cotransporter

2

3

High-throughput

0.553

High

1186065

SOAT
Sodium-dependent organic anion transporter

2

3

High-throughput

0.553

High

1187588

AR13B
ADP-ribosylation factor-like protein 13B

2

1

High-throughput

0.553

High

1210322

MF14B
Hippocampus abundant transcript-like protein 1

2

3

High-throughput

0.553

High

1348550

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.553

High

1351720

GP152
Probable G-protein coupled receptor 152

2

4

High-throughput

0.553

High

1447170

S35C2
Solute carrier family 35 member C2

2

2

High-throughput

0.553

High

1452315

SCN3B
Sodium channel regulatory subunit beta-3

2

1

High-throughput

0.553

High

1452601

KCNK4
Potassium channel subfamily K member 4

2

1

High-throughput

0.553

High

397105

ESR1
Estrogen receptor

2

1

High-throughput

0.521

High

1408207

RNF5
E3 ubiquitin-protein ligase RNF5

1

1

High-throughput

0.515

High

423359

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

638541

FPR1
fMet-Leu-Phe receptor

1

2

High-throughput

0.489

High

848582

MAGA8
Melanoma-associated antigen 8

1

1

High-throughput

0.489

High

867687

GPR12
G-protein coupled receptor 12

1

1

High-throughput

0.489

High

1042789

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

1

High-throughput

0.489

High

1309001

S22A9
Organic anion transporter 7

1

6

High-throughput

0.489

High

1349594

S22A8
Organic anion transporter 3

1

6

High-throughput

0.489

High

1363243

AQP3
Aquaporin-3

1

4

High-throughput

0.489

High

1393092

CREL1
Protein disulfide isomerase CRELD1

1

2

High-throughput

0.489

High

1429302

S22A4
Solute carrier family 22 member 4

1

6

High-throughput

0.489

High

1432438

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

1454000

SC5A6
Sodium-dependent multivitamin transporter

1

3

High-throughput

0.489

High

329676

LERL1
Leptin receptor overlapping transcript-like 1

1

1

High-throughput

0.470

High

1438553

LFG4
Protein lifeguard 4

1

0

High-throughput

0.458

High

386314

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.439

High

549907

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

1

High-throughput

0.439

High

1102462

BIK
Bcl-2-interacting killer

1

1

High-throughput

0.439

High

1207645

F209A
Protein FAM209A

1

1

High-throughput

0.439

High

1431987

IF3M
Translation initiation factor IF-3, mitochondrial

1

2

High-throughput

0.439

High

1446593

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

1

High-throughput

0.439

High

1294277

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

High-throughput

0.437

High

1453998

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1352104

S26A7
Anion exchange transporter

1

1

High-throughput

0.407

High

66538

PCX2
Pecanex-like protein 2

2

0

High-throughput

0.316

High

140014

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

275124

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

0

High-throughput

0.316

High

456024

ASGR2
Asialoglycoprotein receptor 2

2

0

High-throughput

0.316

High

1195277

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.316

High

1281205

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

1310970

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

0

High-throughput

0.316

High

1383363

TM143
Transmembrane protein 143

2

0

High-throughput

0.316

High

1449805

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1212316

TM63B
Mechanosensitive cation channel TMEM63B

1

0

High-throughput

0.279

Low

1244720

TTC33
Tetratricopeptide repeat protein 33

1

0

High-throughput

0.279

Low

1253949

FA83H
Protein FAM83H

1

0

High-throughput

0.279

Low

1413517

DCNL5
DCN1-like protein 5

1

0

High-throughput

0.279

Low

1448670

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.279

Low

1415501

GGACT
Gamma-glutamylaminecyclotransferase

1

0

High-throughput

0.269

Low

1064040

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.268

Low

1452285

TBA8
Tubulin alpha-8 chain

1

0

High-throughput

0.251

Low

251322

NEMF
Ribosome quality control complex subunit NEMF

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025