Protein: CDX2
Homeobox protein CDX-2 (CDX-3) (Caudal-type homeobox protein 2)

Gene: CDX2
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q99626

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000794 - condensed nuclear chromosome
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

685324

PAX6
Paired box protein Pax-6

1

20

Small-scale

0.724

High

1045689

TF65
Transcription factor p65

2

4

Small-scale

0.584

High

1406114

KDM5B
Lysine-specific demethylase 5B

2

9

Small-scale

0.584

High

903240

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

10

Small-scale

0.561

High

1067638

EP300
Histone acetyltransferase p300

1

19

Small-scale

0.561

High

1102236

ATM
Serine-protein kinase ATM

1

1

Small-scale

0.561

High

1315380

CF206
Cilia- and flagella-associated protein 206

2

2

High-throughput

0.553

High

1406112

KR412
Keratin-associated protein 4-12

2

20

High-throughput

0.553

High

133127

FOXE1
Forkhead box protein E1

1

20

High-throughput

0.536

High

189262

IPO8
Importin-8

1

3

High-throughput

0.536

High

280793

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.536

High

334887

IPO7
Importin-7

1

3

High-throughput

0.536

High

595572

H15
Histone H1.5

1

1

High-throughput

0.515

High

635213

HNF1A
Hepatocyte nuclear factor 1-alpha

1

3

Small-scale

0.501

High

668004

CDK2
Cyclin-dependent kinase 2

1

11

Small-scale

0.501

High

903466

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

15

Small-scale

0.501

High

1392038

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

2

Small-scale

0.501

High

1406115

DNM3L
DNA

1

4

Small-scale

0.501

High

902029

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.489

High

892925

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.480

High

1086683

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

Small-scale

0.480

High

50415

MEX3A
RNA-binding protein MEX3A

1

3

Small-scale

0.479

High

564270

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

Small-scale

0.479

High

626342

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.479

High

630005

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

891761

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.479

High

1005014

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.479

High

1217015

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

2

Small-scale

0.479

High

1252371

MEX3B
RNA-binding protein MEX3B

1

2

Small-scale

0.479

High

1380113

FBXW7
F-box/WD repeat-containing protein 7

1

4

Small-scale

0.479

High

1406113

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

550433

PABP1
Polyadenylate-binding protein 1

1

0

Small-scale

0.458

High

1229194

INT3
Integrator complex subunit 3

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025