Protein: THAP3
THAP domain-containing protein 3

Gene: THAP3
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q8WTV1

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0008270 - zinc ion binding
GO:0045944 - positive regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

905452

HCFC1
Host cell factor 1

2

9

Small-scale

0.639

High

185880

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

2

4

Small-scale

0.611

High

787570

TNR3
Tumor necrosis factor receptor superfamily member 3

3

2

High-throughput

0.609

High

422710

A4
Amyloid-beta precursor protein

2

4

High-throughput

0.602

High

965568

NTF2
Nuclear transport factor 2

2

1

High-throughput

0.553

High

502447

H2A1
Histone H2A type 1

1

4

High-throughput

0.536

High

600000

ZNF16
Zinc finger protein 16

1

1

High-throughput

0.536

High

658297

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.536

High

886540

CTCF
Transcriptional repressor CTCF

1

2

High-throughput

0.536

High

987134

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.536

High

994679

YBOX1
Y-box-binding protein 1

1

3

High-throughput

0.536

High

1179698

LIN41
E3 ubiquitin-protein ligase TRIM71

1

5

High-throughput

0.536

High

1275581

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

1

High-throughput

0.536

High

1356124

RENT1
Regulator of nonsense transcripts 1

1

1

High-throughput

0.536

High

1356127

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

High-throughput

0.536

High

1356128

THA11
THAP domain-containing protein 11

1

2

High-throughput

0.536

High

1356142

ZNF70
Zinc finger protein 70

1

2

High-throughput

0.536

High

1356143

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

167334

KLF11
Krueppel-like factor 11

1

4

High-throughput

0.515

High

274680

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.515

High

1096122

TADBP
TAR DNA-binding protein 43

1

1

High-throughput

0.515

High

183039

NKRF
NF-kappa-B-repressing factor

1

0

High-throughput

0.513

High

982495

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.513

High

1356130

ZN184
Zinc finger protein 184

1

0

High-throughput

0.513

High

1356139

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

0

High-throughput

0.513

High

667379

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.493

High

599836

YBOX3
Y-box-binding protein 3

1

3

High-throughput

0.489

High

649379

H1T
Histone H1t

1

3

High-throughput

0.489

High

686304

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.489

High

860568

RS5
Small ribosomal subunit protein uS7

1

1

High-throughput

0.489

High

860856

RS10
Small ribosomal subunit protein eS10

1

1

High-throughput

0.489

High

986124

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.489

High

1063473

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.489

High

1112108

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.489

High

1226028

LAR1B
La-related protein 1B

1

1

High-throughput

0.489

High

1245672

LARP1
La-related protein 1

1

1

High-throughput

0.489

High

1356122

SRS12
Serine/arginine-rich splicing factor 12

1

3

High-throughput

0.489

High

1356131

RM09
Large ribosomal subunit protein bL9m

1

1

High-throughput

0.489

High

1356135

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.489

High

1356136

TSYL2
Testis-specific Y-encoded-like protein 2

1

1

High-throughput

0.489

High

1356146

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.489

High

1356148

RBM19
Probable RNA-binding protein 19

1

2

High-throughput

0.489

High

1356149

HCFC2
Host cell factor 2

1

9

High-throughput

0.489

High

1356126

TRI63
E3 ubiquitin-protein ligase TRIM63

1

7

High-throughput

0.481

High

1356133

TRI55
Tripartite motif-containing protein 55

1

7

High-throughput

0.481

High

1132853

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

2

High-throughput

0.479

High

856830

BAG6
Large proline-rich protein BAG6

1

3

High-throughput

0.470

High

1157477

PKN1
Serine/threonine-protein kinase N1

1

1

High-throughput

0.470

High

1356144

UBQL1
Ubiquilin-1

1

3

High-throughput

0.470

High

1028827

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

1

Small-scale

0.439

High

1356145

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.437

High

1356123

TF2H4
General transcription factor IIH subunit 4

2

0

High-throughput

0.322

High

1356134

UBL5
Ubiquitin-like protein 5

2

0

High-throughput

0.316

High

183489

CASC3
Protein CASC3

2

0

High-throughput

0.313

High

1332194

KRI1
Protein KRI1 homolog

2

0

High-throughput

0.313

High

301133

RL1D1
Ribosomal L1 domain-containing protein 1

1

0

High-throughput

0.279

Low

615892

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.279

Low

683745

PTX3
Pentraxin-related protein PTX3

1

0

High-throughput

0.279

Low

1090264

ELAV2
ELAV-like protein 2

1

0

High-throughput

0.279

Low

1094066

RM28
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.279

Low

1117612

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.279

Low

1245469

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.279

Low

1307380

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.279

Low

1308822

P3H2
Prolyl 3-hydroxylase 2

1

0

High-throughput

0.279

Low

1356129

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.279

Low

1356132

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.279

Low

1356137

OSBL3
Oxysterol-binding protein-related protein 3

1

0

High-throughput

0.279

Low

1356138

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.279

Low

1356140

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.279

Low

1356141

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.279

Low

1356147

NOP16
Nucleolar protein 16

1

0

High-throughput

0.279

Low

159994

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

574387

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.268

Low

574544

TYRO
Tyrosinase

1

0

High-throughput

0.268

Low

577995

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.268

Low

582893

EZRI
Ezrin

1

0

High-throughput

0.268

Low

650318

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

702485

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

702637

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.268

Low

728806

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.268

Low

963338

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.268

Low

988557

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.268

Low

1105897

LSAMP
Limbic system-associated membrane protein

1

0

High-throughput

0.268

Low

1133901

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

1356150

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1356125

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.249

Low

506139

PAB4L
Polyadenylate-binding protein 4-like

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025