Protein: ESTD
S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D) (Methylumbelliferyl-acetate deacetylase) (EC 3.1.1.56)

Gene: ESTD, ESD
Organism: Homo sapiens
Interactions: 52
UniProt ID: P10768

Gene Ontology (top 5):
GO:0005788 - endoplasmic reticulum lumen
GO:0005829 - cytosol
GO:0016788 - hydrolase activity, acting on ester bonds
GO:0018738 - S-formylglutathione hydrolase activity
GO:0031410 - cytoplasmic vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

499379

ESTD
S-formylglutathione hydrolase

4

2

High-throughput

0.893

High

50892

FSD2
Fibronectin type III and SPRY domain-containing protein 2

5

1

High-throughput

0.658

High

381763

G3P
Glyceraldehyde-3-phosphate dehydrogenase

2

0

High-throughput

0.585

High

499389

CRK
Adapter molecule crk

2

2

High-throughput

0.576

High

499383

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

2

0

High-throughput

0.551

High

499394

CAV1
Caveolin-1

2

0

High-throughput

0.547

High

499391

ARP2
Actin-related protein 2

1

1

High-throughput

0.536

High

499399

MYLK
Myosin light chain kinase, smooth muscle

1

1

High-throughput

0.536

High

201188

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

243088

DIAP2
Protein diaphanous homolog 2

1

0

High-throughput

0.513

High

499388

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.513

High

499397

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.513

High

499398

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.513

High

499410

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

499412

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

499416

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

499404

MYLK4
Myosin light chain kinase family member 4

1

1

High-throughput

0.489

High

499392

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.486

High

226348

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

499400

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.479

High

499414

FYV1
1-phosphatidylinositol 3-phosphate 5-kinase

1

1

High-throughput

0.479

High

354260

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

362741

FINC
Fibronectin

1

0

High-throughput

0.458

High

487075

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

499385

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

499393

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

499396

SRSF5
Serine/arginine-rich splicing factor 5

1

0

High-throughput

0.458

High

499403

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

499406

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

499409

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

499413

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

499415

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.458

High

92406

E9PDH4
Phosphoinositide kinase, FYVE-type zinc finger containing

1

1

High-throughput

0.445

High

499401

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

499411

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

499384

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

499407

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

499390

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

306383

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.279

Low

499380

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

499381

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.279

Low

499395

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.279

Low

499402

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

499405

CDKL3
Cyclin-dependent kinase-like 3

1

0

High-throughput

0.279

Low

499408

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

243840

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

329280

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

384159

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

499382

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

499386

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

499387

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024