Protein: SYCE3
Synaptonemal complex central element protein 3 (Testis highly expressed gene 2 protein) (THEG-2)

Gene: SYCE3
Organism: Homo sapiens
Interactions: 70
UniProt ID: A1L190

Gene Ontology (top 5):
GO:0000801 - central element
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0006915 - apoptotic process
GO:0007130 - synaptonemal complex assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

50887

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

3

0

High-throughput

0.634

High

50898

CENPE
Centromere-associated protein E

3

0

High-throughput

0.634

High

50911

CSN6
COP9 signalosome complex subunit 6

3

0

High-throughput

0.634

High

50927

SPAG5
Sperm-associated antigen 5

3

0

High-throughput

0.634

High

50947

SKAP
Small kinetochore-associated protein

3

0

High-throughput

0.634

High

50880

TIF1A
Transcription intermediary factor 1-alpha

2

1

High-throughput

0.628

High

50897

CSN2
COP9 signalosome complex subunit 2

2

1

High-throughput

0.628

High

50899

MTG8
Protein CBFA2T1

2

2

High-throughput

0.628

High

50913

CNTRL
Centriolin

2

1

High-throughput

0.628

High

50936

CSN7B
COP9 signalosome complex subunit 7b

2

1

High-throughput

0.628

High

50886

HAUS5
HAUS augmin-like complex subunit 5

2

0

High-throughput

0.602

High

50892

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

0

High-throughput

0.602

High

50907

HAUS3
HAUS augmin-like complex subunit 3

2

0

High-throughput

0.602

High

50909

SAS6
Spindle assembly abnormal protein 6 homolog

2

0

High-throughput

0.602

High

50924

OMA1
Metalloendopeptidase OMA1, mitochondrial

2

0

High-throughput

0.602

High

50934

CENPH
Centromere protein H

2

0

High-throughput

0.602

High

50935

HAUS4
HAUS augmin-like complex subunit 4

2

0

High-throughput

0.602

High

50937

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

0

High-throughput

0.602

High

50939

HAUS2
HAUS augmin-like complex subunit 2

2

0

High-throughput

0.602

High

50943

FEM1B
Protein fem-1 homolog B

2

0

High-throughput

0.602

High

50945

CE164
Centrosomal protein of 164 kDa

2

0

High-throughput

0.602

High

50923

HAUS1
HAUS augmin-like complex subunit 1

2

0

High-throughput

0.601

High

50902

PKN1
Serine/threonine-protein kinase N1

2

0

High-throughput

0.580

High

50904

LIN41
E3 ubiquitin-protein ligase TRIM71

2

1

High-throughput

0.574

High

50917

NIN
Ninein

2

1

High-throughput

0.574

High

50919

RBCC1
RB1-inducible coiled-coil protein 1

2

1

High-throughput

0.574

High

50882

MTG8R
Protein CBFA2T2

1

2

High-throughput

0.536

High

50884

MTG16
Protein CBFA2T3

1

2

High-throughput

0.536

High

50942

CSN7A
COP9 signalosome complex subunit 7a

1

1

High-throughput

0.536

High

50912

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.513

High

50920

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.513

High

50921

GPKOW
G-patch domain and KOW motifs-containing protein

1

0

High-throughput

0.513

High

50928

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.513

High

50929

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.513

High

50879

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

50894

HD
Huntingtin

1

0

High-throughput

0.493

High

50918

PSMA8
Proteasome subunit alpha-type 8

1

0

Small-scale

0.458

High

50895

INPP
Inositol polyphosphate 1-phosphatase

1

1

High-throughput

0.439

High

50908

ATAD2
ATPase family AAA domain-containing protein 2

1

0

High-throughput

0.426

High

50941

COMD3
COMM domain-containing protein 3

1

0

High-throughput

0.426

High

50948

X5DP77
Inositol polyphosphate-1-phosphatase isoform A

1

1

High-throughput

0.417

High

50930

KIFC3
Kinesin-like protein KIFC3

3

0

High-throughput

0.345

High

50933

YIPF3
Protein YIPF3

3

0

High-throughput

0.345

High

50881

RER1
Protein RER1

2

0

High-throughput

0.328

High

50890

PX11B
Peroxisomal membrane protein 11B

2

0

High-throughput

0.328

High

50891

HBAZ
Hemoglobin subunit zeta

2

0

High-throughput

0.328

High

50900

CAMP2
Calmodulin-regulated spectrin-associated protein 2

2

0

High-throughput

0.328

High

50901

CUL2
Cullin-2

2

0

High-throughput

0.328

High

50903

KIZ
Centrosomal protein kizuna

2

0

High-throughput

0.328

High

50905

VPS53
Vacuolar protein sorting-associated protein 53 homolog

2

0

High-throughput

0.328

High

50910

M3K15
Mitogen-activated protein kinase kinase kinase 15

2

0

High-throughput

0.328

High

50915

HOOK3
Protein Hook homolog 3

2

0

High-throughput

0.328

High

50916

HOME1
Homer protein homolog 1

2

0

High-throughput

0.328

High

50926

SCLT1
Sodium channel and clathrin linker 1

2

0

High-throughput

0.328

High

50938

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

2

0

High-throughput

0.328

High

50940

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.328

High

50946

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.328

High

50906

K2C79
Keratin, type II cytoskeletal 79

2

0

High-throughput

0.316

High

50925

SGF29
SAGA-associated factor 29

2

0

High-throughput

0.316

High

50944

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

High-throughput

0.299

High

50932

TRI54
Tripartite motif-containing protein 54

1

0

High-throughput

0.282

High

50889

SNP29
Synaptosomal-associated protein 29

1

0

High-throughput

0.279

Low

50914

SAPC2
Suppressor APC domain-containing protein 2

1

0

High-throughput

0.279

Low

50922

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.279

Low

50885

WFS1
Wolframin

1

0

High-throughput

0.268

Low

50896

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

50931

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

50883

CCD22
Coiled-coil domain-containing protein 22

1

0

High-throughput

0.232

Low

50888

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.232

Low

50893

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025