HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: UB2L3 (P68036)
Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)
Gene: UBE2L3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019899 - enzyme binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 154
+	Hs
		832796 MCM2_HUMAN (1-904): 0: 1078: 100.00		UB2D4_HUMAN (2-149): 6.75e-76: 224: 38.93
+	Hs
		832248 MCM2_HUMAN (1-904): 0: 1078: 100.00		UB2D1_HUMAN (2-149): 5.66e-75: 221: 38.26
+	Hs
		832324 MCM2_HUMAN (1-904): 0: 1078: 100.00		UB2D2_HUMAN (2-149): 7.95e-75: 221: 37.58
+	Hs
		832290 MCM2_HUMAN (1-904): 0: 1078: 100.00		UB2D3_HUMAN (2-149): 8.29e-74: 218: 36.91
+	Hs
		159034 MCM2_HUMAN (1-904): 0: 1078: 100.00		UB2L6_HUMAN (1-152): 4e-53: 166: 55.26